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Yeshala(SK),Panda(SS),Moharana(L),Saju(SV)... J Ovarian Res 2026-02-07

...BRCA2 in 5(10.9%), and non-BRCA HRD + in 11(23.9%). Olaparib was given to 27(58.7%) and Rucaparib to 19(41.3%). At a med...

Can(ND),Akcay(IM),Celik(E),Ciftci(C),Unal(... Hum Genomics 2026-02-08

...BRCA2, PALB2, CHEK2, and ATM, while in CRC patients PVs were enriched in MLH1, MUTYH, MSH2, and CHEK2. Notably, CHEK2 wa...

Cui(H),Zhu(M),Ling(B),Zhang(L) Am J Cancer Res None

...BRCA2 NM_000059.3:c.439C>A, were identified in the Chinese population. These findings provide a biological rationale to ...

Ito(F),Kobayashi(K),Hayashi(G),Kamijo(S),F... Urol Case Rep 2026-03-00

...BRCA2-mutated mCRPC who achieved a sustained complete response to olaparib monotherapy. After progression on androgen de...

Lang(GT),Weng(XL),Liu(Y),Hu(X),Shao(ZM),Hu(Z) Pathophysiology 2026-01-20

...BRCA2, and PALB2 variants, we delineated the genomic landscape of 96 MaBC cases. Subsequent whole-exome sequencing (WES)...

Ishida(H),Takashima(A) Cureus 2026-01-00

...BRCA2 variants. RRSO has been shown to markedly reduce the risk of ovarian cancer and to confer a protective effect agai...

Feng(W),Zhang(D),Feng(H),Zhao(C),He(J),Tan... Phytomedicine 2026-04-00

...Brca2 and Rad51, and disrupted chromosome pairing. SCENIC regulatory network analysis suggested that KDM5A is functional...

Wang(Z),Qiu(M),Liu(D),Yu(Y),Gu(D),Zhang(F)... RSC Med Chem 2026-01-16

...BRCA2-deficient DLD-1 cells (IC50 = 1.16 μM), which was about 5-fold more potent than the reversible analog C10 (IC50 = ...

Bancroft(EK),Page(EC),McHugh(J),Thomas(S),... Eur Urol 2026-05-00

...BRCA2 PGV carriers (915 BRCA1, 901 BRCA2); and (2) age-matched noncarriers for a familial PGV (727 BRCA1 and 520 BRCA2 n...

Germain(LS),Ott(BP),Hindmarch(CCT),Winn(LM... Environ Epigenet None

...brca2 gene, a key DNA damage enzyme. Integration of RNA-seq and WGBS datasets identified nine genes with both expression...