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Wang(Y),Domecq(C),Cuggia(A),Mejia-Garcia(A... J Med Genet 2026-06-25

...BRCA2 and PALB2 increase lifetime risk of developing breast (BC), ovarian (OC) and pancreatic (PC) cancer. They have bee...

Tamindarov(K),Frank(M),Wegscheider(S),Bene... Front Oncol None

...BRCA2 and CHEK2. The contribution of mismatch repair (MMR) genes such as MSH6 to MBC risk remains, however, unclear. In ...

Scafetta(R),Troiano(R),Gullotta(C),Guarino... Eur J Cancer 2026-05-15

...BRCA2), and 21 of these patients received denosumab. Among patients not receiving denosumab, BRCA1/2-wild-type/unknown p...

Huang(Y),Gao(Y),Duan(Z),Jia(X),Sun(Y),Liu(... NPJ Genom Med 2026-04-02

...BRCA2. Importantly, 28 variants across 12 genes showed significant allele frequency divergence between Chinese and Europ...

Lin(JH),Wu(H),Tang(XY),Masson(E),Stenson(P... HGG Adv 2026-07-09

...BRCA2 c.8331+2T>C, illustrating how intermediate splicing effects complicate clinical interpretation across distinct gen...

Terrano(V),Perri(E),Cioffo(C),Mastroianni(... Int Cancer Conf J 2026-04-00

...BRCA2, ATM, and TP53. Due to the high TMB, off-label Pembrolizumab was initiated. Radiological evaluations at 3 and 6 mo...

Corso(G),Andreon(C),La Vecchia(C),Bottazzo... Eur J Cancer 2026-05-15

...BRCA2 (SOR=1.28, 95%CI (0.95-1.72)). The difference between the association with BRCA1 and BRCA2 was statistically signi...

Chapman(IG),Wu(X),Veuger(S),Jowsey(PA) PLoS One None

...BRCA2 and RAD51 to DNA double strand breaks (DSBs) during HRR, though the magnitude of this defect in human cells is not...

Zhao(Q),Li(N),Marinovic(E),McInerny(S),Zet... NPJ Breast Cancer 2026-04-04

Pathogenic coding variants in BRCA1, BRCA2 and PALB2 confer hereditary breast/ovarian cancer risk, yet these regions com...

Milano(L),Wells(S),Vaitsiankova(A),Drummon... Mol Cell 2026-04-16

...BRCA2 and is associated with the BRCA2-dependent accumulation of RAD51 recombinase in chromatin. Our data identify nasce...