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Barsch(M),Godbole(I),Metzger(P),Benzing(M)... ESMO Gastrointest Oncol 2026-06-00

...BRCA2-mutated BTC together with a positive HRD score was sensitive to platinum-based therapy and poly (ADP-ribose) polym...

Lin(C),Hu(J),Cai(F),Chen(J),Huang(J),Lin(Y... Curr Med Chem 2026-03-18

...BRCA2, and ESR1 as key hub genes. These genes were upregulated in tumors, showing robust diagnostic performance (AUC>0.7...

Zeng(Z),Gandini(A),Bhatt(R),Proctor(M),Goh... Br J Cancer 2026-06-00

...BRCA2 mutation and homologous recombination repair status in vitro. In vivo, treatment significantly reduced tumour burd...

Silvestri(V),Valentini(V),Bucalo(A),Porzio... Breast Cancer Res 2026-04-07

...BRCA2 (n = 26), BRCA1 (n = 12), and PALB2 (n = 3). Immune characterization included PD-1 and PD-L1 expression, immune sc...

Sapp(JC),Lewis(KL),Modlin(EW),Davidson(A),... Am J Hum Genet 2026-05-07

...BRCA2-related cancer predisposition. Our estimates of the likelihood of a valid clinicomolecular diagnosis ranged from 2...

Smith(JE),Wang(KJ),Kennedy(EM),Munday(JC),... Nature 2026-06-00

...BRCA2-dependent VSG recombination with patterns identical to those observed during infection. These newly generated VSGs...

Pehrsson(M),Jakkula(E),Ala-Kulju(K),Loukol... Cancer Epidemiol Biomarkers... 2026-06-02

...BRCA2, and PALB2 genes predisposing to hereditary breast and ovarian cancer (HBOC), from biobank samples. PVs of BRCA1, ...

Wong(H),Korsakova(A),Wu(AJ),Kularatnarajah... Cancer Res 2026-07-02

...BRCA2 loss. Segments assigned to an HER2+ enriched signature strongly overlapped regions of chromothripsis and circular ...

Gootzen(TA),Hermens(RP),van Gelder(MM),Hei... J Natl Cancer Inst 2026-04-07

...BRCA2) chose RRS/DO or salpingo-oophorectomy with or without hormonal replacement therapy (HRT). We compared QoL (Greene...

Hu(C),Sahu(S),Chen(W),Galloux(M),Richardso... Nat Commun 2026-04-09

...BRCA2 variants as pathogenic (n = 735) or benign (n = 5191) and provides valuable insights for individuals with BRCA2 va...