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TP53 BRCA1 CRISPR single-cell cancer

Rosa-Rosa(Juan Manuel),Pita(Guillermo),Urios… Am J Hum Genet 2009-03-23

...BRCA2, and in other breast-cancer-susceptibility genes, account for about 25% of familial breast cancer. Linkage studies...

Metcalfe(Kelly A) Womens Health (Lond) 2009-03-30

Owing to the significant breast cancer risk associated with BRCA1 or BRCA2 mutations, women with these mutations have se...

Panchal(Seema M),Ennis(Marguerite),Canon(San… BMC Med Genet 2009-01-30

...BRCA2 mutation. We evaluated the performances of currently-used risk models among patients from a large familial program...

Landi(Stefano) Mutat Res 2009-04-15

...BRCA2 (breast-ovarian familial cancer), where PC is part of the cancer spectrum of the disease. In addition, in this rev...

Hashemian(Amir H),Hajizadeh(Ebrahim),Kazemne… Saudi Med J 2009-07-14

...BRCA2 specific gene mutations in Iranian women with breast cancer.,We conducted this study in the Department of Biostati...

Jankowski(Stéphane),Currie-Fraser(Erica),Xu(… J Biomol Tech 2009-04-02

...BRCA2, and MMR (MLH1/MSH2 genes) and the 9p21 chromosomal region. MLPA polymerase chain reaction products were separated...

Rebbeck(Timothy R),Kauff(Noah D),Domchek(Sus… J Natl Cancer Inst 2009-02-02

Risk-reducing salpingo-oophorectomy (RRSO) is widely used by carriers of BRCA1 or BRCA2 (BRCA1/2) mutations to reduce th...

Flanagan(James M),Munoz-Alegre(Marta),Hender… Hum Mol Genet 2009-05-18

...BRCA2, CHEK2, ATM, ESR1, SFN, CDKN2A, TP53, GSTP1, CDH1, CDH13, HIC1, PGR, SFRP1, MLH1, RARB and HSD17B4. We show that t...

Magnusson(Susanne),Borg(Ake),Kristoffersson(… Fam Cancer 2009-01-09

...BRCA2 (n=43) MMR (MLH1, MSH2 MSH6) (n=31) and CDKN2A (n=15) genes in comparison with population based control families (...

Ginsburg(Ophira),Ghadirian(Parviz),Lubinski(… Breast Cancer Res Treat 2009-02-17

Among women with a mutation in BRCA1 or BRCA2, the risk of breast cancer is high, but it may be modified by exogenous an...

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