Risk-reducing salpingo-oophorectomy (RRSO) is widely used by carriers of BRCA1 or BRCA2 (BRCA1/2) mutations to reduce th...
...Brca2, or combined Lig4/Xrcc2 during neural development using Nestin-cre. In all cases, inactivation of these repair fac...
Owing to the significant breast cancer risk associated with BRCA1 or BRCA2 mutations, women with these mutations have se...
...BRCA2 mutation. We evaluated the performances of currently-used risk models among patients from a large familial program...
...BRCA2, CCND1, ERCC1, ERCC2, ERCC4, ERCC5, MGMT, NBN, PARP1, POLI, TP53, XPA, XRCC1, XRCC2, XRCC3, and XRCC4). XRCC1, XRC...
...BRCA2 (breast-ovarian familial cancer), where PC is part of the cancer spectrum of the disease. In addition, in this rev...
...BRCA2 specific gene mutations in Iranian women with breast cancer.,We conducted this study in the Department of Biostati...
...BRCA2 status, 19 were BRCA2 mutation positive. In survival analysis, BRCA2 gene mutation status (P = 0.02) and clinicopa...
...BRCA2, p16/CDKN2A, STK11 and PRSS1. Individuals can be tested for germline mutations in these genes; however, until rece...
...BRCA2 gene. All men who reviewed the decision aid indicated that they would recommend the booklet to other men in the sa...
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