...BRCA2 mutations (BRCA-positive) were selected from our database and matched (1:2) with 44 nonhereditary EOC controls (de...
...BRCA2 tumor suppressor is important in maintaining genomic stability. BRCA2 is proposed to control the availability, cel...
...BRCA2) in the two age groups suggests differences in their molecular pathogenesis and dysregulation of multiple DNA repa...
...BRCA2 promoter. These results indicate that Parp-1 down-regulates BRCA2 expression through an interaction with a repress...
...BRCA2 mutation carriers are less clear.,Case patients were 1,469 women from Los Angeles County ages 20 to 49 years with ...
...BRCA2. Of those with a mutation, 23 had no history of cancer and 21 had a breast cancer diagnosis. Analysis of the 44 pa...
...BRCA2 arises from the distinct functions served by their products in DNA repair or mitosis, explains many features of ca...
...BRCA2, in the homologous recombination (HR) pathway for DNA double-strand break (DSB) repair suggests that the mechanism...
...BRCA2 mutation carriers has only been investigated in a small number of studies.,We used data on 2,281 BRCA1 carriers an...
...BRCA2 are the major genes for high-penetrance familial breast and ovarian cancer, whereas mutations in ATM or Chek2 conf...
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