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Breast cancer in young women (YBC): prevalence of BRCA1/2 mutations and risk of…

Haffty(B G),Choi(D H),Goyal(S),Silber(A),Ran… Ann Oncol 2009-12-07

...BRCA2, compared with CA and KO. VUS were predominantly in BRCA2 and AA had markedly higher frequency of VUS (38%) compar...

The Drosophila hus1 gene is required for homologous recombination repair during…

Peretz(Gabriella),Arie(Lihi Gur),Bakhrat(Ann… Mech Dev 2009-12-14

...brca2 homologue, which was shown to participate in DNA repair during meiosis. Together, our results imply that hus1 is r...

BRCA1 and BRCA2 germline mutations in Korean ovarian cancer patients.

Lim(Myong Cheol),Kang(Sokbom),Seo(Sang-Soo),… J Cancer Res Clin Oncol 2009-09-29

...BRCA2 by direct sequencing.,Sixteen percent (54/337) of patients had a strong family history. Of the 54 patients with a ...

The yield of first-time endoscopic ultrasonography in screening individuals at …

Poley(J W),Kluijt(I),Gouma(D J),Harinck(F),W… Am J Gastroenterol 2009-10-01

...BRCA2 mutation carriers with familial clustering of PC, and 1 individual had a p53 mutation. Three (6.8%) patients had a...

Contribution of BRCA1 germ-line mutations to breast cancer in Greece: a hospita…

Armaou(S),Pertesi(M),Fostira(F),Thodi(G),Ath… Br J Cancer 2009-07-08

...BRCA2, with early-onset cases generally considered as an indicator of genetic susceptibility. Specific BRCA1 and BRCA2 m...

Attendance of men at the familial cancer clinic: what they value from the consu…

Lobb(Elizabeth Anne),Gaff(Clara L),Meiser(Be… Genet Med 2009-09-25

...BRCA2 mutation completed a self-administered questionnaire.,Seventy- two percent (72%) of men attended the familial canc...

Age at onset of bilateral breast cancer, the presence of hereditary BRCA1, BRCA…

Skasko(Elzbieta),Kluska(Anna),Niwińska(Anna)… Onkologie 2009-06-16

...BRCA2 and CHEK2 gene mutations with reference to their positive family history of cancer.,The DNA of peripheral blood ly...

Role of Blm and collaborating factors in recombination and survival following r…

Mao(Ninghui),Kojic(Milorad),Holloman(William… DNA Repair (Amst) 2009-08-06

...BRCA2 homolog, suppressed toxicity to hydroxyurea caused by loss of Blm function. However, differential suppression by B...

LKB1 catalytic activity contributes to estrogen receptor alpha signaling.

Nath-Sain(Suchita),Marignani(Paola A) Mol Biol Cell 2009-10-27

...BRCA2. In this study, we investigate the role of LKB1 in estrogen receptor alpha (ERalpha) signaling. We demonstrate for...

PALB2 is an integral component of the BRCA complex required for homologous reco…

Sy(Shirley M H),Huen(Michael S Y),Chen(Junji… Proc Natl Acad Sci U S A 2009-06-05

...BRCA2, binds directly to BRCA1, and serves as the molecular scaffold in the formation of the BRCA1-PALB2-BRCA2 complex. ...

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