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TP53 BRCA1 CRISPR single-cell cancer

Sakai(Wataru),Swisher(Elizabeth M),Jacquemon… Cancer Res 2009-09-15

...BRCA2 due to another secondary BRCA2 mutation. BRCA2 depletion sensitized BRCA2-restored PEO1 clones and PEO4 to cisplat...

Evans(D Gareth R),Lalloo(Fiona),Ashcroft(Lin… Cancer Epidemiol Biomarkers P… 2009-10-20

...BRCA2 (28%) carriers but in both groups tended to occur within the first 2 years after gene test (except in the youngest...

Dombernowsky(Sarah Louise),Weischer(Maren),F… Cancer Epidemiol Biomarkers P… 2009-10-20

BRCA1 and BRCA2 are key tumor suppressors with a role in cellular DNA repair, genomic stability, and checkpoint control....

Ahmed(Munaza),Lalloo(Fiona),Evans(D Gareth) Expert Rev Anticancer Ther 2009-12-03

...BRCA2, a number of moderate-penetrance genes and, more recently, common low-penetrance genes and loci. The clinical bene...

McWilliams(Robert R),Bamlet(William R),de An… Cancer Epidemiol Biomarkers P… 2009-12-15

Inherited risk of pancreatic cancer has been associated with mutations in several genes, including BRCA2, CDKN2A (p16), ...

Armaou(S),Pertesi(M),Fostira(F),Thodi(G),Ath… Br J Cancer 2009-07-08

...BRCA2, with early-onset cases generally considered as an indicator of genetic susceptibility. Specific BRCA1 and BRCA2 m...

Su(Yeyang),Lin(Lin),Tian(Geng),Chen(Chen),Li… Sci China C Life Sci 2009-09-17

...BRCA2 as target regions, specifically designed LBA primer pairs to amplify and randomly ligate them. 70 target sequences...

Jonsdottir(Asta Björk),Vreeswijk(Maaike P G)… Cell Oncol 2009-07-23

...BRCA2 gene.,Cell divisions were monitored with time lapse live-cell imaging. BRCA2 mRNA expression levels in BRCA2+/- an...

Haffty(B G),Choi(D H),Goyal(S),Silber(A),Ran… Ann Oncol 2009-12-07

...BRCA2, compared with CA and KO. VUS were predominantly in BRCA2 and AA had markedly higher frequency of VUS (38%) compar...

Poley(J W),Kluijt(I),Gouma(D J),Harinck(F),W… Am J Gastroenterol 2009-10-01

...BRCA2 mutation carriers with familial clustering of PC, and 1 individual had a p53 mutation. Three (6.8%) patients had a...

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