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TP53 BRCA1 CRISPR single-cell cancer

Evans(D Gareth R),Lalloo(Fiona),Ashcroft(Lin… Cancer Epidemiol Biomarkers P… 2009-10-20

...BRCA2 (28%) carriers but in both groups tended to occur within the first 2 years after gene test (except in the youngest...

Thompson(Larry H),Hinz(John M) Mutat Res 2009-09-29

...BRCA2 and FANCN/PALB2 proteins act at an early step. We conclude that the core subcomplex is required for both TLS and H...

Shivji(Mahmud K K),Mukund(Shreyas R),Rajendr… Proc Natl Acad Sci U S A 2009-09-21

...BRCA2 controls the enzyme RAD51 during homologous DNA recombination (HDR) to preserve genome stability. BRCA2 binds to R...

Goodheart(M J),Rose(S L),Hattermann-Zogg(M),… Clin Genet 2009-12-09

...BRCA2 mutations have been identified. We hypothesize that sequence variants of the BRCA2 gene are common in CCC of the o...

Seong(M-W),Cho(Si),Noh(D-Y),Han(W),Kim(S-W),… Clin Genet 2009-12-09

...BRCA2 genes are the strongest susceptibility genes identified for breast cancer worldwide. However, BRCA1/BRCA2 have bee...

Soumittra(Nagasamy),Meenakumari(Balaiah),Par… Hered Cancer Clin Pract 2009-12-29

Hereditary cancers account for 5-10% of cancers. In this study BRCA1, BRCA2 and CHEK2*(1100delC) were analyzed for mutat...

Llorente(Bertrand),Modesti(Mauro) Mol Cell 2009-12-16

...BRCA2 tumor suppressor function.

Mazloum(Nayef),Holloman(William K) Mol Cell 2009-12-16

...BRCA2 family protein in Ustilago maydis. Using plasmid DNA and a homologous duplex oligonucleotide with 5' protruding si...

De Nicolo(Arcangela),Parisini(Emilio),Zhong(… Cancer Res 2009-11-17

...BRCA2 sequence change. An increasing number of variants of uncertain significance (VUS) are being identified, the unclas...

Sinilnikova(O M),Antoniou(A C),Simard(J),Hea… Br J Cancer 2009-10-28

...BRCA2-mediated carcinogenesis. A single nucleotide polymorphism (SNP) in the promoter region of MDM2 (309T>G, rs2279744)...

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