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Eprenetapopt in combination with carboplatin in high-grade ovarian and triple...

Pineda(B),Martinez-Pretel(JJ),Sanchez-Serr... Front Oncol None

...BRCA2 and TP53, which are associated with chemotherapy sensitivity. Olaparib, a PARP inhibitor, provides the greatest cl...

A case of breast acinar cell carcinoma combined with metaplastic carcinoma.

Liu(S),Hu(H) Discov Oncol 2026-04-20

...BRCA2, and others. CONCLUSION: This report describes a breast tumor exhibiting concurrent features of AcCC and matrix-pr...

A comparative study of molecular characteristics of pathogenic and uncertain ...

Guan(J),Hu(J),Lin(S),Chen(C),Luo(Y),Zhou(W... BMC Res Notes 2026-04-20

...BRCA2 were each detected in 3 cases; (3) In breast cancer patients carrying BRCA and BRCA1 mutations, the negative rates...

ATM promotes PFKP nuclear translocation to balance glycolysis and homologous ...

Liu(H),Zhang(M),Xu(Z),Yang(Z),Pan(Y),Bai(Y... Nucleic Acids Res 2026-04-13

...BRCA2 interaction and HR efficiency. Clinically, PFKP exhibits significant nuclear accumulation in diabetes-associated m...

BRCA2, a conserved Rad51 mediator lost in ascomycetes.

Tsubouchi(H),Iwasaki(H) Trends Genet 2026-07-00

...BRCA2 was restricted to higher eukaryotes. However, the identification of BRCA2 homologs across diverse fungal phyla rev...

Prevalence of recurrent and non-recurrent BRCA1 and BRCA2 pathogenic variants...

Matkowski(R),Abrahamowska(M),Michalowska(D... BMC Cancer 2026-04-21

...BRCA2) were identified in 30 patients (2.94%; 95% CI: 2.07%–4.16%, Wilson). The most frequent variant was BRCA1 c.5266du...

Multilocus Inherited Neoplasia Alleles Syndrome in a Patient With BRCA2-Assoc...

Avila-Rodriguez(V),Ruiz-Patiño(A),Bonilla-... Case Rep Oncol Med None

...BRCA2, MLH1, MSH2, MSH6, PMS2, APC, TP53, PTEN, and STK11, conferring a higher risk of multiple primary malignancies. We...

Preoperative breast cancer screening before chest masculinization surgery.

Schuster(CR),Aslami(ZV),Taccheri(C),Azizi(... Breast Cancer Res Treat 2026-04-22

...BRCA2 mutation (2.3%, n = 1). Imaging revealed irregular findings in 17.1% (n = 7), with malignancy confirmed in 2 patie...

A lasso-based model combining miRNA and clinical variables predicts future ri...

Webber(JW),Wollborn(L),Mishra(S),Alimena(S... Sci Rep 2026-03-24

...BRCA2. However, most women with HBOC are undiagnosed, and some patients meeting clinical criteria for HBOC will have no ...

Phase II study of olaparib and durvalumab in patients with metastatic castrat...

Li(C),Madan(RA),Lee(MJ),Lee(S),Sato(N),Ras... J Immunother Cancer 2026-03-25

...BRCA2 variants experienced longer rPFS (13.2 months; 95% CI 7.7 to 20.2 months) than patients without BRCA2 variants (4....

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