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Distinct roles of BARD1 isoforms in mitosis: full-length BARD1 mediates Aurora …

Ryser(Stephan),Dizin(Eva),Jefford(Charles Ed… Cancer Res 2009-03-23

...BRCA2. We used selective small interfering RNAs to distinguish the functions of FL BARD1 and BARD1beta. Depletion of FL ...

Increased expression of BRCA2 and RAD51 in lymph node metastases of canine mamm…

Klopfleisch(R),Gruber(A D) Vet Pathol 2009-07-10

...BRCA2, and RAD51 mRNA expression was quantified in highly defined laser microdissected tissue samples of simple adenomas...

High prevalence of preinvasive lesions adjacent to BRCA1/2-associated breast ca…

Arun(Banu),Vogel(Kristen J),Lopez(Adriana),H… Cancer Prev Res (Phila) 2009-03-31

Mutations in BRCA1 and BRCA2 increase a woman's lifetime risk of developing breast cancer by 43% to 84%. It was original...

Estimated risk of radiation-induced breast cancer from mammographic screening f…

Berrington de Gonzalez(Amy),Berg(Christine D… J Natl Cancer Inst 2009-03-06

...BRCA2 mutation carriers. If we assume that the mortality reduction from mammography is 15%-25% or less for young women, ...

Two mutations of BRCA2 gene at exon and splicing site in a woman who underwent …

Pensabene(M),Spagnoletti(I),Capuano(I),Conde… Ann Oncol 2009-06-02

...BRCA2 protein in its carboxy-terminal region.,The two BRCA2 mutations identified affect mRNA splicing fidelity and play ...

Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer.

McCabe(N),Cerone(M A),Ohishi(T),Seimiya(H),L… Oncogene 2009-04-01

The BRCA1 and BRCA2 proteins are involved in the maintenance of genome stability and germ-line loss-of-function mutation...

DNA-binding Domain within the Brh2 N Terminus Is the Primary Interaction Site f…

Zhou(Qingwen),Kojic(Milorad),Holloman(Willia… J Biol Chem 2009-05-26

...BRCA2 homolog in Ustilago maydis, is highly conserved and aligns with the DSS1/DNA-binding domain (DBD) of mammalian BRC...

A method to assess the clinical significance of unclassified variants in the BR…

Gómez García(Encarna B),Oosterwijk(Jan C),Ti… Breast Cancer Res 2009-06-23

...BRCA2 are in agreement with published information of them being neutral. The p.R2784W variant in BRCA2 remains uncertain...

Unraveling the next chapter: sexual development, body image, and sexual functio…

Matloff(Ellen T),Barnett(Rachel E),Bober(Sha… Cancer J 2009-04-21

...BRCA2 has become available in the past 15 years, and it has been established that female BRCA carriers have a high lifet...

A review of the clinical relevance of mismatch-repair deficiency in ovarian can…

Pal(Tuya),Permuth-Wey(Jenny),Sellers(Thomas … Cancer 2008-09-08

...BRCA2 mutations. An epigenetic mechanism known to cause inactivation of the MMR system is promoter hypermethylation of 1...

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