...BRCA2 orthologue (dmbrca2; CG30169) has been identified by sequence similarity, no functional data addressing the role o...
...BRCA2 analyses conducted in breast and ovarian cancer families were focused on identification of mutations in coding seq...
...BRCA2 germ-line mutation are at very high risk of breast and/or ovarian cancer. Because high-quality data are lacking fr...
...BRCA2-related), but frequent in sporadic cancers in organs where Li-Fraumeni-related carcinogenesis is common e.g. adren...
...BRCA2- RAD51 is limited.,Here, the author performs an analysis to study the molecular structure of human BRCA2-RAD51 com...
...BRCA2. We also show that BRCA2 interacts with RPN3 and RPN7 and that the BRCA2/RPN7 interaction is independent of DSS1. ...
High penetrance genes such as BRCA1 or BRCA2 account for only a small proportion of familial breast cancer in Chinese po...
...BRCA2 mutation-negative families, a germline TP53 13398 G>A (Arg213Gln) mutation was identified, which was selected for ...
...BRCA2 were identified. After pathologic review, focal areas of normal breast epithelium, atypical ductal hyperplasia, du...
The BRCA2 tumor suppressor functions in repair of DNA by homologous recombination through regulating the action of Rad51...
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