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TP53 BRCA1 CRISPR single-cell cancer

Lu(Huimei),Yue(Jingyin),Meng(Xiangbing),Nick… Nucleic Acids Res 2008-01-18

...BRCA2- and p21-interacting protein, BCCIP, regulates BRCA2 and RAD51 nuclear focus formation, DSB-induced HR and cell cy...

Frosk(Patrick),Burgess(Susan),Dyck(Tamara),J… Genet Test 2008-01-15

Mutations in BRCA1 and BRCA2 account for about 40% of families with an inherited susceptibility to breast and/or ovarian...

Lubitz(Rebecca Jean),Komaromy(Miriam),Crawfo… Genet Test 2008-01-15

...BRCA2 mutations involves teaching about hereditary cancer, genetics and risk, subjects that are difficult to grasp and a...

Debniak(T),Scott(R J),Górski(B),Cybulski(C),… Eur J Cancer 2008-04-14

...BRCA2 and CHEK2 with malignant melanoma (MM). We genotyped 630 unselected MM patients and over 3700 controls (newborns, ...

Staton(Ashley D),Kurian(Allison W),Cobb(Kris… Fam Cancer 2008-10-09

Women with mutations in the BRCA1 or BRCA2 cancer susceptibility genes face unique choices regarding management of their...

Yarden(Ronit I),Friedman(Eitan),Metsuyanim(S… Breast Cancer Res Treat 2008-11-13

...BRCA2 alleles in inherited breast and ovarian cancer cases among Ashkenazi-Jewish (AJ) women. We genotyped several subse...

Iarmarcovai(G),Bonassi(S),Botta(A),Baan(R A)… Mutat Res 2008-07-31

...BRCA2 mutations (with or without breast cancer) show enhanced sensitivity to clastogens. Some evidence further suggests ...

Mannen(Taro),Andoh(Tomoko),Tani(Tokio) Biochem Biophys Res Commun 2008-01-10

...BRCA2, a tumor suppressor protein, in humans. The Schizosaccharomyces pombe strain lacking the dss1(+) gene (Deltadss1) ...

Ghataorhe(Pavandeep),Kurian(Allison W),Picka… Cancer Genet Cytogenet 2008-01-22

...BRCA2. To our knowledge, this is the first report of a patient with both MEN1 and BRCA2 mutations and with a personal hi...

Schmutzler(R K) Verh Dtsch Ges Pathol 2008-01-25

...BRCA2, have been identified and account for a risk of up to 80% for breast cancer and up to 40% for ovarian cancer. Mole...

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