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Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations.

Fackenthal(James D),Olopade(Olufunmilayo I) Nat Rev Cancer 2008-01-03

...BRCA2 tumour-suppressor genes are strong predictors of breast and/or ovarian cancer development. The contribution of the...

Improving sequence variant descriptions in mutation databases and literature us…

Wildeman(Martin),van Ophuizen(Ernest),den Du… Hum Mutat 2008-02-06

...BRCA2, and HbVar databases were analyzed, showing that 87%, 25%, and 38%, respectively, were error-free and following th...

BRCA1 and BRCA2 mutations in an Asian clinic-based population detected using a …

Ang(Peter),Lim(Irene H K),Lee(Tze-Chuen),Luo… Cancer Epidemiol Biomarkers P… 2008-05-16

Genetic testing for germ line mutations in the BRCA1 and BRCA2 genes for some families at high risk for breast and/or ov...

Gene-specific selection against experimental fanconi anemia gene inactivation i…

Gallmeier(Eike),Hucl(Tomas),Calhoun(Eric S),… Cancer Biol Ther 2008-02-28

...BRCA2 or FANCD2, acting downstream in the FA pathway. Targeting of the second allele in in BRCA2 and FANCD2 heterozygote...

Implication of BRCA2 -26G>A 5' untranslated region polymorphism in susceptibili…

Gochhait(Sailesh),Bukhari(Syed Irfan Ahmad),… Breast Cancer Res 2008-03-11

...BRCA2 can modulate the fine-tuned regulation of the multifunctional gene BRCA2 and renders risk or protection according ...

Genetic instability syndromes with progeroid features.

Neveling(K),Bechtold(A),Hoehn(H) Z Gerontol Geriatr 2008-02-12

...BRCA2 breast cancer gene. Unlike cells from any other human disorder, FA cells are uniquely sensitive to oxidative stres...

The DNA damage signalling kinase ATM is aberrantly reduced or lost in BRCA1/BRC…

Tommiska(J),Bartkova(J),Heinonen(M),Hautala(… Oncogene 2008-05-01

...BRCA2 are also components of the genome maintenance network and their mutations predispose to breast cancer, we have exa...

BARD1 variants are not associated with breast cancer risk in Australian familia…

Gorringe(Kylie L),Choong(David Y H),Visvader… Breast Cancer Res Treat 2008-11-13

...BRCA2. These families were ascertained in Australia through the Kathleen Cunningham Foundation Consortium for Research i...

Smoking and risk of breast cancer in carriers of mutations in BRCA1 or BRCA2 ag…

,, Breast Cancer Res Treat 2008-11-13

...BRCA2. However, the effect of cigarette smoking on breast cancer risk in mutation carriers is the subject of conflicting...

BRCA1 and BRCA2 germline mutation analysis in the Indonesian population.

Purnomosari(Dewajani),Pals(Gerard),Wahyono(A… Breast Cancer Res Treat 2008-03-04

...BRCA2 respectively, are novel. Several novel, pathogenic BRCA1 and BRCA2 germline mutations are found in early onset Ind...

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