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TP53 BRCA1 CRISPR single-cell cancer

Ramus(Susan J),Harrington(Patricia A),Pye(Ca… Hum Mutat 2008-01-28

...BRCA2 genes. Deleterious BRCA1 mutations were identified in 104 families (37%) and BRCA2 mutations in 25 families (9%). ...

Akbari(M R),Malekzadeh(R),Nasrollahzadeh(D),… Oncogene 2008-03-12

...BRCA2 might play a role in the etiology of ESCC. We screened for mutations in the coding region of the BRCA2 gene in the...

Kadouri(Luna),Hubert(Ayala),Rotenberg(Yakir)… J Med Genet 2008-03-06

...BRCA2 carriers. The HR for lymphoma was 11.9 (95% CI 3.1 to 46.2, p = 0.001) in BRCA2 carriers. Risk estimates for other...

Honrado(Emiliano),Osorio(Ana),Milne(Roger L)… Mod Pathol 2008-02-20

...BRCA2 genes. The search for other genes has until now failed, probably because there is not one single BRCAX gene, but r...

Chand(Manish),Moore(Patrick J),Clarke(Andrew… World J Surg Oncol 2008-02-05

...BRCA2 genes are at an increased risk of developing breast, ovarian and peritoneal cancer. Primary peritoneal carcinoma i...

Li(Wen-Feng),Hu(Zhen),Rao(Nan-Yan),Song(Chua… Breast Cancer Res Treat 2008-08-05

To have an overview of the role of BRCA1 and BRCA2 genes among Chinese high-risk breast cancer patients, we analyzed 489...

Evans(D Gareth R),Howell(Anthony) Breast Cancer Res 2008-03-11

...BRCA2? What are her risks of developing breast cancer with or without such a mutation? These risks taken together with t...

Grant(Stephen G),Das(Rubina),Cerceo(Christin… Pathol Oncol Res 2008-05-05

...BRCA2 (FANCD1) confers increased susceptibility to DNA double strand breaks, but this genotype occurs only in the tumor ...

Moro(Loredana),Arbini(Arnaldo A),Yao(Jorge L… Cancer Sci 2008-04-22

BRCA2 is a multifunctional tumor suppressor protein which plays critical roles in DNA repair, transcription, and cell pr...

Han(X),Saito(H),Miki(Y),Nakanishi(A) Oncogene 2008-08-06

...BRCA2 gene cause inherited susceptibility to breast and ovarian cancers. BRCA2 contains two nuclear localization signals...

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