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Moghadasi(S),Monajemi(R),Braspenning(ME),V... Hum Genet 2026-03-26

...BRCA2 and PALB2 genes, which can be used as an important component of the ACMG/AMP (the American College of Medical Gene...

Park(W),O'Connor(CA),Chou(JF),Hilmi(M),Tar... Nat Med 2026-05-00

Homologous recombination deficiency (HRD) arising from BRCA1or BRCA2 or PALB2 mutations confers sensitivity to platinum ...

Płotka(A),Marcinkowska-Swojak(M),Rakoczy(M... J Appl Genet 2026-03-26

...BRCA2, FANCM), kinase signaling (JAK2, NF1), and chromatin remodeling (CREBBP, BARD1), as well as the gene ontology term...

Clark(PM),Thompson(CB),Schultz(KA) Nucleosides Nucleotides Nuc... 2026-03-26

...BRCA2 loss and mutant p53 further heighten this vulnerability. This review synthesizes mechanistic evidence linking dCK ...

Udobi(ME),Chinedu(SN),Afolabi(IS),Ezike(KN... Front Oncol None

...BRCA2, alongside luminal regulators like GATA3, decline progressively with both advancing age and tumor aggressiveness, ...

Gislinge(JIP),Byrjalsen(A),Naver(KV),Claus... Fam Cancer 2026-03-27

...BRCA2 PV, 55 had PVs in moderate-risk genes, and 277 were enrolled based on family history of OC ± BC alone. Of these 27...

Ekinci(B),Orenay-Boyacioglu(S),Erdogdu(IH)... Biomedicines 2026-02-25

...BRCA2, and KMT2C. Notably, PIK3CA mutations were significantly more frequent in geriatric patients (28.3% vs. 23.2%, p =...

Hah(YS),Lee(SJ),Hwang(J),Choi(HY) Biomedicines 2026-03-08

...BRCA2 and HLA associations). Methods: We conducted a narrative, evidence-based synthesis of peer-reviewed epidemiologic ...

Bu(R),Haqawi(W),Razzaq(EAA),Azam(S),Iqbal(... Int J Mol Sci 2026-03-14

...BRCA2, FANCA, SLX4, RAD50, MSH6, POLD1 and NF1. Four patients (36.4%) carried PVs/LPVs in canonical FA pathway genes; th...

Tsyganov(MM),Bulatova(DZ),Fedorenko(AA),Lo... Curr Issues Mol Biol 2026-03-04

...BRCA2, contributes to genomic instability and the development of more aggressive tumor clones. The use of chemical carci...