Mutations in BRCA1 and BRCA2 genes are associated with family predisposition to breast and ovarian cancer. Novel screeni...
...BRCA2) germline mutation carriers. To test the hypothesis, human peripheral blood lymphocytes of BRCA carriers with and ...
...BRCA2, MLH1, MSH2, MSH6 and TP53), although their orthologs have arisen in different points of evolution. Our results de...
...BRCA2 mutations are associated with a greatly increased risk for development of hereditary breast cancer (HBC). Besides ...
...BRCA2-defective cells. We exposed cells defective in the HR component XRCC3 (irs1SF) and BRCA2 (V-C8) and their parental...
...BRCA2 mutations have been identified in some families and a mutation in the palladin gene has been shown to segregate wi...
...BRCA2 in mammary tumors obtained from dogs.,Blood samples, mammary gland specimens, or mammary tumors from 3 tumor-beari...
...BRCA2 mutations. Study participants included individuals with known deleterious mutations in BRCA1 or BRCA2 and individu...
...BRCA2 homolog and its modifier Dss1 rather than Rad52 as a mediator of Rad51, the presence of only a single Rad51 paralo...
To evaluate the prevalence of BRCA1 and BRCA2 mutations and associations with clinical correlates of disease in a popula...
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