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Immunohistochemical classification of non-BRCA1/2 tumors identifies different g…

Honrado(Emiliano),Osorio(Ana),Milne(Roger L)… Mod Pathol 2008-02-20

...BRCA2 genes. The search for other genes has until now failed, probably because there is not one single BRCAX gene, but r...

Novel complex genomic rearrangement of the BRCA1 gene.

Zikan(Michal),Pohlreich(Petr),Stribrna(Jana)… Mutat Res 2008-03-13

...BRCA2 analyses conducted in breast and ovarian cancer families were focused on identification of mutations in coding seq...

Contribution of the BRCA1 and BRCA2 mutations to breast cancer in Tunisia.

Troudi(Wafa),Uhrhammer(N),Sibille(C),Dahan(C… J Hum Genet 2008-01-09

...BRCA2 genes responsible for up to 30% of these. To investigate the prevalence of BRCA1 and BRCA2 gene mutations in breas...

Assessing breast cancer risk and BRCA1/2 carrier probability.

Culver(Julie),Lowstuter(Katrina),Bowling(Lau… Breast Dis 2008-01-03

...BRCA2, the two genes most commonly implicated in hereditary breast cancer. We review BRCA1 and BRCA2 mutations in variou...

Susceptibility to breast cancer: hereditary syndromes and low penetrance genes.

Nusbaum(Rachel),Vogel(Kristen J),Ready(Kayle… Breast Dis 2008-01-03

...BRCA2; however, other less common gene mutations which confer elevated breast cancer risk are associated with Cowden syn...

The DNA damage signalling kinase ATM is aberrantly reduced or lost in BRCA1/BRC…

Tommiska(J),Bartkova(J),Heinonen(M),Hautala(… Oncogene 2008-05-01

...BRCA2 are also components of the genome maintenance network and their mutations predispose to breast cancer, we have exa...

Genetic instability syndromes with progeroid features.

Neveling(K),Bechtold(A),Hoehn(H) Z Gerontol Geriatr 2008-02-12

...BRCA2 breast cancer gene. Unlike cells from any other human disorder, FA cells are uniquely sensitive to oxidative stres...

The predominant role of surgery in the prevention and new trends in the surgica…

Fatouros(Michael),Baltoyiannis(Georgios),Rou… Ann Surg Oncol 2008-02-21

...BRCA2 germ-line mutation are at very high risk of breast and/or ovarian cancer. Because high-quality data are lacking fr...

Distant disease-free interval, site of first relapse and post-relapse survival …

Kriege(Mieke),Seynaeve(Caroline),Meijers-Hei… Breast Cancer Res Treat 2008-10-14

...BRCA2-associated breast cancer (BC) patients are as yet scarcely available.,We identified 57 BRCA1-associated and 31 BRC...

BCCIP regulates homologous recombination by distinct domains and suppresses spo…

Lu(Huimei),Yue(Jingyin),Meng(Xiangbing),Nick… Nucleic Acids Res 2008-01-18

...BRCA2- and p21-interacting protein, BCCIP, regulates BRCA2 and RAD51 nuclear focus formation, DSB-induced HR and cell cy...

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