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Genetic variation in the DNA repair genes is predictive of outcome in lung canc…

Matakidou(Athena),el Galta(Rachid),Webb(Emil… Hum Mol Genet 2008-01-24

...BRCA2/FA pathway genes as determinants of OS was provided by an analysis restricted to the 456 patients treated with pla...

Integrative mining of traditional Chinese medicine literature and MEDLINE for f…

Zhou(Xuezhong),Liu(Baoyan),Wu(Zhaohui),Feng(… Artif Intell Med 2008-02-01

...BRCA2 (breast cancer 2, early onset), to demonstrate the preliminary results. The underlying hypothesis is that the rela...

Hereditary breast cancer: pathobiology, clinical translation, and potential for…

Rubinstein(Wendy S) Fam Cancer 2008-07-08

...BRCA2 breast cancers bodes well for the development of targeted cancer therapies. Cells with BRCA1 or BRCA2 loss of func...

BRCA1, BRCA2, TP53, and CDKN2A germline mutations in patients with breast cance…

Monnerat(Christian),Chompret(Agnès),Kannengi… Fam Cancer 2008-03-28

...BRCA2 deleterious mutation, the other one a BRCA2 unclassified variant), and two carriers of a CDKN2A germline mutation....

Heterogenic loss of the wild-type BRCA allele in human breast tumorigenesis.

King(Tari A),Li(Weiwei),Brogi(Edi),Yee(Cindy… Ann Surg Oncol 2008-01-24

...BRCA2 were identified. After pathologic review, focal areas of normal breast epithelium, atypical ductal hyperplasia, du...

Management options after prophylactic surgeries in women with BRCA mutations: a…

Allain(Dawn C),Sweet(Kevin),Agnese(Doreen M) Cancer Control 2008-09-02

...BRCA2 genes, which are also associated with an increased risk of ovarian cancer. Increased surveillance, chemoprevention...

Breast cancer risk-assessment models.

Evans(D Gareth R),Howell(Anthony) Breast Cancer Res 2008-03-11

...BRCA2? What are her risks of developing breast cancer with or without such a mutation? These risks taken together with t...

BRCA1 and BRCA2 mutations in an Asian clinic-based population detected using a …

Ang(Peter),Lim(Irene H K),Lee(Tze-Chuen),Luo… Cancer Epidemiol Biomarkers P… 2008-05-16

Genetic testing for germ line mutations in the BRCA1 and BRCA2 genes for some families at high risk for breast and/or ov...

Improving sequence variant descriptions in mutation databases and literature us…

Wildeman(Martin),van Ophuizen(Ernest),den Du… Hum Mutat 2008-02-06

...BRCA2, and HbVar databases were analyzed, showing that 87%, 25%, and 38%, respectively, were error-free and following th...

Haplotype patterns in cancer-related genes with long-range linkage disequilibri…

Ribas(Gloria),Milne(Roger L),Gonzalez-Neira(… Eur J Hum Genet 2008-04-22

...BRCA2, ERCC6, MLH1, MSH3, RAD54B and XRCC4) relative to the other 101 cancer-related genes studied (P=1.23 x 10(-6)). Th...

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