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[Molecular genetics and clinics of hereditary breast cancer].

Schmutzler(R K) Verh Dtsch Ges Pathol 2008-01-25

...BRCA2, have been identified and account for a risk of up to 80% for breast cancer and up to 40% for ovarian cancer. Mole...

A carrier of both MEN1 and BRCA2 mutations: case report and review of the liter…

Ghataorhe(Pavandeep),Kurian(Allison W),Picka… Cancer Genet Cytogenet 2008-01-22

...BRCA2. To our knowledge, this is the first report of a patient with both MEN1 and BRCA2 mutations and with a personal hi...

Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations.

Fackenthal(James D),Olopade(Olufunmilayo I) Nat Rev Cancer 2008-01-03

...BRCA2 tumour-suppressor genes are strong predictors of breast and/or ovarian cancer development. The contribution of the...

Genetic polymorphisms and micronucleus formation: a review of the literature.

Iarmarcovai(G),Bonassi(S),Botta(A),Baan(R A)… Mutat Res 2008-07-31

...BRCA2 mutations (with or without breast cancer) show enhanced sensitivity to clastogens. Some evidence further suggests ...

Cancer risk reduction and reproductive concerns in female BRCA1/2 mutation carr…

Staton(Ashley D),Kurian(Allison W),Cobb(Kris… Fam Cancer 2008-10-09

Women with mutations in the BRCA1 or BRCA2 cancer susceptibility genes face unique choices regarding management of their...

MDM2 SNP309 accelerates breast and ovarian carcinogenesis in BRCA1 and BRCA2 ca…

Yarden(Ronit I),Friedman(Eitan),Metsuyanim(S… Breast Cancer Res Treat 2008-11-13

...BRCA2 alleles in inherited breast and ovarian cancer cases among Ashkenazi-Jewish (AJ) women. We genotyped several subse...

Dss1 associating with the proteasome functions in selective nuclear mRNA export…

Mannen(Taro),Andoh(Tomoko),Tani(Tokio) Biochem Biophys Res Commun 2008-01-10

...BRCA2, a tumor suppressor protein, in humans. The Schizosaccharomyces pombe strain lacking the dss1(+) gene (Deltadss1) ...

Implementation of genetics to personalize medicine.

Chung(Wendy K) Gend Med 2008-01-15

...BRCA2, maturity onset diabetes of youth, diabetes, hemochromatosis, coronary artery disease, copy number changes, geneti...

Common variants of DNA repair genes and malignant melanoma.

Debniak(T),Scott(R J),Górski(B),Cybulski(C),… Eur J Cancer 2008-04-14

...BRCA2 and CHEK2 with malignant melanoma (MM). We genotyped 630 unselected MM patients and over 3700 controls (newborns, ...

Functional analysis of Drosophila melanogaster BRCA2 in DNA repair.

Brough(Rachel),Wei(Debbie),Leulier(Sophie),L… DNA Repair (Amst) 2008-05-30

...BRCA2 orthologue (dmbrca2; CG30169) has been identified by sequence similarity, no functional data addressing the role o...

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