Germline mutations of BRCA1 and BRCA2 account for the majority of hereditary breast cancers, many of which are classifie...
The co-existence of mutations in the BRCA1 and BRCA2 genes is unusual, and to date almost all cases reported have had at...
...BRCA2 mutations. Seventeen pathogenic BRCA2 and four BRCA1 mutations were identified (34%) in samples from an affected f...
Pathogenic mutations in BRCA1 and BRCA2 have been reported in about 55-59% of breast and ovarian cancer (HBOC) families ...
...BRCA2 being the two major genes responsible for this inherited risk. In order to evaluate the proportion of high-risk Fr...
...BRCA2 genes. Their relative performance in a clinical setting is unclear.,To compare the performance characteristics of ...
...BRCA2 mutation-negative families, a germline TP53 13398 G>A (Arg213Gln) mutation was identified, which was selected for ...
...BRCA2- RAD51 is limited.,Here, the author performs an analysis to study the molecular structure of human BRCA2-RAD51 com...
...BRCA2 and Rad51, individually and as a complex, in breast cancer.,Expression of BRCA1, BRCA2 and Rad51 was investigated ...
...BRCA2 might play a role in the etiology of ESCC. We screened for mutations in the coding region of the BRCA2 gene in the...
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