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A novel breast cancer-associated BRIP1 (FANCJ/BACH1) germ-line mutation impairs…

De Nicolo(Arcangela),Tancredi(Mariella),Lomb… Clin Cancer Res 2008-09-16

...BRCA2 mutation, were screened for BRIP1 mutations. Functional analyses, including coimmunoprecipitation and stability as...

The 3020insC NOD2 gene mutation in patients with ovarian cancer.

Magnowski(Piotr),Medrek(Krzysztof),Magnowska… Ginekol Pol 2008-11-18

...BRCA2 genes are responsible for an increased risk of ovarian cancer. The role of mutations in NOD2 gene in this type of ...

Clinically applicable models to characterize BRCA1 and BRCA2 variants of uncert…

Spearman(Andrew D),Sweet(Kevin),Zhou(Xiao-Pi… J Clin Oncol 2008-12-24

...BRCA2 mutations. Study participants included individuals with known deleterious mutations in BRCA1 or BRCA2 and individu...

International registries of families at high risk of pancreatic cancer.

Greenhalf(William),Malats(Nuria),Nilsson(Mag… Pancreatology 2008-12-17

...BRCA2 mutations have been identified in some families and a mutation in the palladin gene has been shown to segregate wi...

BRCA mutation-negative women from hereditary breast and ovarian cancer families…

Bakos(Alexis D),Hutson(Sadie P),Loud(Jennife… Health Expect 2008-11-10

...BRCA2 mutation test negative for the family mutation, it is assumed that they will transition their personal cancer risk...

Novel variations and loss of heterozygosity of BRCA2 identified in a dog with m…

Yoshikawa(Yasunaga),Morimatsu(Masami),Ochiai… Am J Vet Res 2008-11-18

...BRCA2 in mammary tumors obtained from dogs.,Blood samples, mammary gland specimens, or mammary tumors from 3 tumor-beari...

Impaired tamoxifen metabolism reduces survival in familial breast cancer patien…

Newman(William G),Hadfield(Kristen D),Latif(… Clin Cancer Res 2008-10-08

...BRCA2) with familial breast cancer who had been treated with 20-mg tamoxifen following surgery.,Eight (7%) individuals h...

Association of common PALB2 polymorphisms with breast cancer risk: a case-contr…

Chen(Peizhan),Liang(Jie),Wang(Zhanwei),Zhou(… Clin Cancer Res 2008-10-08

...BRCA2-mediated DNA double-strand break repair and intra-S phase DNA damage checkpoint control, and its mutations are mod...

BRCA1/2 in high-risk African American women with breast cancer: providing genet…

Pal(Tuya),Vadaparampil(Susan),Betts(Judy),Mi… Genet Test 2008-12-11

...BRCA2 (BRCA1/2) in a sample of African American women, recruited through a variety of methods.,We conducted a study inve...

Genetic heterogeneity by comparative genomic hybridization in BRCAx breast canc…

Mangia(Anita),Chiarappa(Patrizia),Tommasi(St… Cancer Genet Cytogenet 2008-06-03

...BRCA2) were analyzed by comparative genomic hybridization (CGH) to investigate intratumor heterogeneity. This was the fi...

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