Genetic testing for the breast and ovarian cancer susceptibility genes BRCA1 and BRCA2 has important implications for th...
...BRCA2 mutations have a substantially increased risk of breast and ovarian cancer compared with the general population. T...
Inhibitors of poly (ADP-ribose)-polymerase-1 (PARP) are highly lethal to cells with deficiencies in BRCA1, BRCA2 or othe...
...BRCA2-associated repressor protein. The aim was to investigate gene copy numbers of CCND1 and EMSY and to determine if C...
...BRCA2 homolog and its modifier Dss1 rather than Rad52 as a mediator of Rad51, the presence of only a single Rad51 paralo...
...BRCA2, have a greatly increased risk of developing breast and/or ovarian cancer. The incidence of BRCA gene mutation is ...
...BRCA2, respectively, were more sensitive to artesunate than the corresponding wild-type. This was also true for XR-V15B ...
...BRCA2-deficient cells.
...BRCA2), and the rearranged during transfection protooncogene RET which is responsible for multiple endocrine neoplasia t...
...BRCA2 genes were cloned, much has been learned about the function of these two major causes of familial breast cancer. B...
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