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In vitro phosphorylation of BRCA2 by the checkpoint kinase CHEK2.

Kim(S),Mohapatra(G),Haber(D A) Br J Cancer 2008-11-04

Germline mutations in both BRCA2 and CHEK2 are associated with an increased risk for male breast cancer. To search for p...

[Mutational analysis of BRCA1 and BRCA2 genes in early-onset breast cancer pati…

Song(Chuan-gui),Hu(Zhen),Yuan(Wen-tao),Di(Ge… Zhonghua Yi Xue Za Zhi 2008-02-20

...BRCA2, all causing no alteration of amino acid coding. The prevalence of BRCA1 and BRCA2 mutations in the patients with ...

Does tumorigenesis select for or against mutations of the DNA repair-associated…

van der Heijden(Michiel S),Brody(Jonathan R)… BMC Genet 2008-03-17

...BRCA2 and MRE11 proteins participate in the repair of double-strand DNA breaks by homologous recombination. Germline BRC...

[Functions of FANCL in primordial germ cell formation and Fanconi anemia].

Zhao(Qing-Guo),Lu(Bai-Song),Huang(Pei-Tang) Yi Chuan Xue Bao 2008-08-18

...BRCA2 to repair DNA damage. In early embryo stage, FA pathway is probably involved in proliferation of PGCs. Mice defici...

Dynamics of DNA repair suggested by the subcellular localization of Brca1 and B…

Huber(L Julie),Chodosh(Lewis A) J Cell Biochem 2008-02-01

...Brca2, may mediate the assembly of protein complexes involved in the repair of damaged DNA, we have performed subcellula...

From adjuvant to preventive breast cancer treatment: bridging the gap over trou…

Ricevuto(E),Di Rocco(Z C),Sidoni(T),Ficorell… Ann Oncol 2008-02-14

...BRCA2 status) and with respect to menopausal status. BC patients, harboring a BRCA1/2 predisposition, may represent the ...

BRCA1 and BRCA2 genetic testing in Italian breast and/or ovarian cancer familie…

Capalbo(C),Ricevuto(E),Vestri(A),Ristori(E),… Ann Oncol 2008-02-14

...BRCA2 gene (472insA, E33X, C1630X and IVS6+1G>C). Twenty-seven of the 99 probands harbored BRCA1 (n = 15) and BRCA2 (n =...

Mutation analysis of five candidate genes in familial breast cancer.

Marsh(Anna),Healey(Sue),Lewis(Aaron),Spurdle… Breast Cancer Res Treat 2008-01-09

Most of the known breast cancer susceptibility genes (BRCA1, BRCA2, CHEK2 and ATM) are involved in the damage response p...

The role of the BRCA2 gene in susceptibility to prostate cancer revisited.

Ostrander(Elaine A),Udler(Miriam S) Cancer Epidemiol Biomarkers P… 2008-12-16

...BRCA2 mutation-carrying families. Additionally, population-based screens of early-onset prostate cancer patients have su...

Five recurrent BRCA1/2 mutations are responsible for cancer predisposition in t…

Krajc(Mateja),Teugels(Erik),Zgajnar(Janez),G… BMC Med Genet 2008-09-26

...BRCA2 gene). The IVS16-2A>G in the BRCA2 gene appears to be a unique founder mutation in the Slovenian population. A pra...

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