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BRCA1- and BRCA2-deficient cells are sensitive to etoposide-induced DNA double-…

Treszezamsky(Alejandro D),Kachnic(Lisa A),Fe… Cancer Res 2007-09-11

The function of BRCA1 and BRCA2 in DNA repair could affect the sensitivity of cells to cytotoxic agents, and would there...

Activation of BTAK expression in primary ovarian surface epithelial cells of pr…

Zhang(Zhihong),Singh(Meenakshi),Davidson(Sus… Mod Pathol 2007-12-18

...BRCA2 mutation (we called BRCA1/2 mutation) are known to predispose to the development of ovarian cancer; however, the m...

Androgens and estrogens in the etiology and prevention of breast cancer.

Muti(Paola),Rogan(Eleanor),Cavalieri(Ercole) Nutr Cancer 2007-06-25

...BRCA2 susceptibility genes, familial history of breast cancer, age, higher socioeconomic status, ionizing radiation, tal...

Surveillance for familial breast cancer: Differences in outcome according to BR…

Moller(Pal),Evans(D Gareth),Reis(Marta M),Gr… Int J Cancer 2007-10-04

...BRCA2+ve or mutation-negative). Breast cancer was diagnosed in 442 patients subsequently followed for a total of 2095 ye...

Cancer yield of mammography, MR, and US in high-risk women: prospective multi-i…

Lehman(Constance D),Isaacs(Claudine),Schnall… Radiology 2007-09-12

...BRCA2 carriers or with at least a 20% probability of carrying a BRCA1/BRCA2 mutation. All imaging modalities were perfor...

Suppression of polyploidy by the BRCA2 protein.

Sagulenko(Evgeny),Savelyeva(Larissa),Ehemann… Cancer Lett 2007-12-20

...BRCA2, and found that BRCA2 acts to suppress polyploidy. Compared with MX-1, the ectopically BRCA2-expressing cells had ...

Prospective study of Outcomes in Sporadic versus Hereditary breast cancer (POSH…

Eccles(Diana),Gerty(Sue),Simmonds(Peter),Ham… BMC Cancer 2007-10-15

...BRCA2 gene carriers and were diagnosed with their first breast cancer during the study recruiting period.,Power estimate...

Rare germline mutations in the BRCA2 gene are associated with early-onset prost…

Agalliu(I),Karlins(E),Kwon(E M),Iwasaki(L M)… Br J Cancer 2007-10-19

...BRCA2 mutations. The coding regions, intron-exon boundaries, and potential regulatory elements of the BRCA2 gene were se...

Identification of women with an increased risk of developing radiation-induced …

Cardis(Elisabeth),Hall(Janet),Tavtigian(Sean… Breast Cancer Res 2007-09-14

...BRCA2, ATM or CHEK2 may double the risk of radiation-induced contralateral breast cancer following radiotherapy for a fi...

The Fanconi anemia pathway promotes homologous recombination repair in DT40 cel…

Takata(Minoru),Yamamoto(Kazuhiko),Matsushita… Subcell Biochem 2007-07-31

...BRCA2/FancD1, or BRIP1/FancJ. These proteins are proposed to function in a common biochemical process (FA pathway), howe...

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