...BRCA2, p53 and other genes. We propose that carriers of such DDR defects may be more prone to malignancy due to 'conditi...
...BRCA2 mutation-negative index patients of 571 German BC families and 712 control individuals.,No significant differences...
BRCA2 rearrangements are rare genetic events. A large BRCA2 genomic insertion was recurrently observed in our participan...
...BRCA2 predispose individuals to breast cancer, a consequence of the role of BRCA2 in DNA repair. Human BRCA2 interacts w...
...BRCA2 gene. More generally, genetic counseling, including screening for BRCA2 mutations, should become standard practice...
...BRCA2 and TP53 mutations, DPC4/SMAD4/MADH4 inactivation, etc.). All the genetic changes observed in PanINs are also foun...
...BRCA2 gene alterations. In the present study, we show by RT-PCR and direct sequencing analysis the occurrence of seven n...
One of the primary purposes of genetic testing for mutations in the BRCA1 and BRCA2 genes in patients with familial brea...
...BRCA2 mutations in a male relative, now deceased, who had early onset (under the age of 55) prostate cancer. The breast ...
...BRCA2 is becoming an increasingly important part of clinical practice. Classification of rare nontruncating sequence var...
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