The BRCAPRO model, used to predict a family's likelihood of carrying a BRCA1 or BRCA2 mutation, was designed using mutat...
The identification of the two major breast cancer susceptibility genes BRCA1 and BRCA2 has led to an explosion of work c...
...BRCA2 are well-established causes of hereditary breast cancer. As genetic testing becomes more widespread, increasing nu...
...BRCA2, has dramatically increased, as has our understanding of prevention options for high-risk women. Effective strateg...
...BRCA2, or one of the mismatch repair (MMR) genes associated with Lynch/HNPCC syndrome. Additionally, we outline ongoing ...
...BRCA2, facilitates tumorigenesis. However, the direct effects of BRCA2 heterozygosity remain unclear. Here, BRCA2 hetero...
...BRCA2, associated with Hereditary Breast/Ovarian Cancer syndrome, have up to an 85% lifetime risk of breast cancer and u...
...BRCA2, PALB2 and BRIP1. Increasing evidence shows that FA proteins function as signal transducers and DNA-processing mol...
...BRCA2 in MBC, we investigated whether the BRCA2 N372H variant, representing the only common non-synonymous polymorphism ...
...BRCA2 regulates Rad51. Here, we show that CeBRC-2, which is only one tenth the size of mammalian BRCA2, complemented BRC...
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