For women who carry a mutation in BRCA1 or BRCA2, the risk of breast cancer is up to 87% by the age of 70. There are opt...
...BRCA2, and found that BRCA2 acts to suppress polyploidy. Compared with MX-1, the ectopically BRCA2-expressing cells had ...
...BRCA2. How this complex interacts with damaged DNA is unknown, as only the FA core protein FANCM (the homolog of an arch...
...BRCA2 expression.,The data indicated that low protein expression of BRCA1 and BRCA2 was frequent in lung adenocarcinomas...
Several epidemiologic studies have reported that carriers of germline mutations in the BRCA2 gene have an increased risk...
...BRCA2 mutations. A total of 10 carriers from 180 families were identified, suggesting that BRCA2 mutations account for 6...
...BRCA2 account for the majority of hereditary breast/ovarian cancer cases. The analysis of BRCA1 gene was carried out in ...
Rare inactivating mutations in BRCA1, BRCA2, ATM, TP53 and CHEK2 confer relative risks for breast cancer between about 2...
As sequence analysis for BRCA1 and BRCA2 mutations is both time- and cost-intensive, current strategies often include sc...
...BRCA2 mutations, or carriers of mismatch repair gene mutations in the hereditary nonpolyposis colorectal cancer group) a...
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