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Pal(LR),Schäffer(AA),Avila(S),Wooten(J),Bu... Res Sq 2026-02-02

...BRCA2/somatic TP53 and germline BRCA1/somatic TP53 (n=40 and n=38 studies, respectively). Statistical testing was perfor...

Bancroft(EK),Page(EC),McHugh(J),Thomas(S),... Eur Urol 2026-05-00

...BRCA2 PGV carriers (915 BRCA1, 901 BRCA2); and (2) age-matched noncarriers for a familial PGV (727 BRCA1 and 520 BRCA2 n...

Leonard(SM),Pearson(CR),Roos(WP),Sobol(RW) Toxics 2026-02-10

...BRCA2 mutant tumors. USP1 is a deubiquitylating enzyme responsible for the removal of the mono-ubiquitin mark on FANCD2,...

Iida(K),Urabe(F),Matsui(Y),Tashiro(K),Yosh... NPJ Precis Oncol 2026-02-26

...BRCA2 pathogenic variants (P = 0.008). Within BRCA2-altered cases, BRCA2 loss was associated with the most favorable OS ...

Edmunds(K),Arora(S),Teppala(S),Scuffham(P)... Fam Cancer 2026-01-24

...BRCA2, BRCA1 and DNA MMR genes for men with metastatic PCa. Thematic analysis of HP/R comments revealed three main topic...

Morozumi(K),Nakamura(Y),Oikawa(M),Iwamura(... Urol Oncol 2026-09-00

...BRCA2 alterations have been associated with aggressive disease, the clinical significance of BRCA2 protein expression fo...

Dell'Elice(A),Palmarini(C),Anaclerio(F),Pi... J Med Genet 2026-07-24

...BRCA2. Nevertheless, a substantial proportion of individuals with strong familial cancer aggregation remain genetically ...

Sherigar(P),Kedlaya Herga(S),Pai(A),Mailan... Cancer Med 2026-07-00

...BRCA2 genes. Yet, the role of other cancer susceptibility genes highlights the genetic etiology of HBOC as complex, thus...

Anjum(RS),Takabe(K) World J Oncol 2026-08-00

...BRCA2)-mutant tumors, impaired RAD51 loading produces profound sensitivity to DNA-damaging agents. However, accumulating...

Chen(JL),Kang(ML),Lin(CJ),Lo(YH),Chen(YJ),... Am J Hum Genet 2026-08-06

...BRCA2 and MLH1 suggest recurrent selective trade-offs in DNA repair genes. Phenome-wide association analysis across 30 h...