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Genetic susceptibility for breast cancer: how many more genes to be found?

Oldenburg(R A),Meijers-Heijboer(H),Corneliss… Crit Rev Oncol Hematol 2007-08-16

...BRCA2. However, these genes explain less than 5% of the total breast cancer incidence, even though several studies have ...

Novel germline mutations in BRCA2 gene among 96 hereditary breast and breast-ov…

Syamala(Vani),Sreeja(Leelakumari),Syamala(Vo… J Cancer Res Clin Oncol 2007-12-11

Aim of the present study was to identify the genetic heterogeneity, prevalence and frequency of germline mutations of BR...

Incidence of BRCA1 and BRCA2 mutations in 54 Chilean families with breast/ovari…

Gallardo(Marcela),Silva(Antonia),Rubio(Loren… Breast Cancer Res Treat 2007-01-16

Our aim was to analyze the incidence of mutations in BRCA1 and BRCA2 genes in 54 families with breast/ovarian cancer. Fa...

Polymorphisms of the BRCA2 and RAD51 genes in breast cancer.

Sliwinski(Tomasz),Krupa(Renata),Majsterek(Ir… Breast Cancer Res Treat 2007-09-19

...BRCA2-Met1915Thr Thr/Thr and BRCA2-Met784Val Met/Met homozygous variants increased the risk. Therefore, the Met1915Thr p...

High incidence of 4153delA BRCA1 gene mutations in Lithuanian breast- and breas…

Gronwald(Jacek),Elsakov(Pavel),Górski(Bohdan… Breast Cancer Res Treat 2007-09-19

...BRCA2 gene mutations confer a high lifetime risk to breast and ovarian cancers. We have screened cancer patients from 13...

Variation in cisplatinum sensitivity is not associated with Fanconi Anemia/BRCA…

Snyder(Eric R),Ricker(Justin L),Chen(Zhong),… Cancer Lett 2007-04-05

...BRCA2. FANC pathway function was evaluated by western blotting for FANCD2 mono-ubiquitination. All of the cell lines wer...

Cancer genetics knowledge and beliefs and receipt of results in Ashkenazi Jewis…

Kelly(Kimberly),Leventhal(Howard),Marvin(Mon… Cancer Control 2007-11-01

...BRCA2 mutations (mutations associated with increased risk of breast-ovarian cancer) endeavors to communicate information...

High incidence of BRCA1-2 germline mutations, previous breast cancer and famili…

Biron-Shental(T),Drucker(L),Altaras(M),Bernh… Eur J Surg Oncol 2007-01-30

...BRCA2). The analysis was performed on genomic DNA extracted from whole blood or paraffin embedded normal tissue of these...

Insulin-like growth factor-1 genotype predicts breast volume after pregnancy an…

Jernström(H),Sandberg(T),Bågeman(E),Borg(A),… Int J Gynecol Cancer 2007-03-15

...BRCA2 mutation carriers, 54 women were noncarriers from BRCA1/2 families, 111 women belonged to breast cancer families w...

The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-dri…

Demidov(O N),Kek(C),Shreeram(S),Timofeev(O),… Oncogene 2007-05-31

...Brca2. This tumor-prone phenotype of Wip1 is fully eliminated through attenuation of proliferation by activating the MKK...

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