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FANCD2 monoubiquitination and activation by hexavalent chromium [Cr(VI)] exposu…

Vilcheck(Susan K),Ceryak(Susan),O'Brien(Trav… Mutat Res 2007-01-03

...BRCA2 (FANCD1) and RAD51. Some forms of hexavalent chromium [Cr(VI)] are implicated as respiratory carcinogens and induc...

Evaluation of BRCA1 and BRCA2 mutation prevalence, risk prediction models and a…

Simard(Jacques),Dumont(Martine),Moisan(Anne-… J Med Genet 2007-06-07

...BRCA2 in a large series of families with breast cancer in the French-Canadian population of Quebec, Canada are reported....

BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer be…

Haile(Robert W),Thomas(Duncan C),McGuire(Val… Cancer Epidemiol Biomarkers P… 2007-06-20

...BRCA2 mutation carriers before age 50. For BRCA2 mutation carriers, use of oral contraceptives may be associated with an...

Molecular genetics and related developments in pancreatic cancer.

Hruban(R H),Goggins(M),Kern(S E) Curr Opin Gastroenterol 2007-07-03

...BRCA2 (7%) tumor suppressor genes. An understanding of the molecular genetics of carcinoma of the pancreas is important ...

The role of hereditary nonpolyposis colorectal cancer in the management of fami…

Farrell(Carolyn),Lyman(Mollie),Freitag(Kathe… Genet Med 2007-01-09

...BRCA2 genes. Hereditary nonpolyposis colorectal cancer, another common syndrome, is also associated with ovarian cancer ...

MDM2 SNP309 accelerates familial breast carcinogenesis independently of estroge…

Wasielewski(Marijke),Nagel(Jord H A),Brekelm… Breast Cancer Res Treat 2007-11-27

...BRCA2. Cancer acceleration was indeed observed in early-onset familial breast cancer cases (diagnosed

High proportion of BRCA1/2 founder mutations in Hispanic breast/ovarian cancer …

Torres(Diana),Rashid(Muhammad Usman),Gil(Fab… Breast Cancer Res Treat 2007-08-02

...BRCA2 mutation for 40% of all BRCA2 mutations. Haplotype analyses suggested that each of these mutations has arisen from...

Phenocopies in BRCA1 and BRCA2 families: evidence for modifier genes and implic…

Smith(A),Moran(A),Boyd(M C),Bulman(M),Shento… J Med Genet 2007-01-30

...BRCA2 mutation but also by modifier genes. One manifestation of this would be the presence of phenocopies in BRCA1/BRCA2...

Molecular genetics of ductal pancreatic neoplasia.

Su(G H),Kern(S E) Curr Opin Gastroenterol 2007-07-03

...BRCA2 genes occur late in the neoplastic progression. Tumor-suppressor genes inactivated in pancreatic cancer such as AL...

The P1812A and P25T BRCA1 and the 5164del4 BRCA2 mutations: occurrence in high-…

Kaufman(Bella),Laitman(Yael),Carvalho(Marcel… Genet Test 2007-06-18

Founder mutations in the BRCA1 and BRCA2 genes have been discovered in the Ashkenazic Jewish population, but a founder m...

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