...Brca2 exon 27 to cells reduced for Blm expression and find that the Brca2- and Blm-impaired cells exhibit genotoxic prof...
...BRCA2. TP53(+/-) matched-pair cell lines were used to determine if knockdown of BRCA1, BRCA2, or validated hits that ass...
...BRCA2-associated breast cancer. However, studies in mouse models reveal that Parp1-null mutation results in genetic inst...
...BRCA2) was in the male patient. The 55 non-truncating variants included 3 unclassified variants predicted to affect prot...
...BRCA2. p(life) and p(mut) were calculated with MENDEL, BRCAPRO(Claus), BRCAPRO(Ford), as well as the Tyrer-Cuzick model....
...BRCA2 carriers are unknown.,We assessed breast cancer risk in a large series of 1,187 BRCA1 and 414 BRCA2 carriers from ...
Genetic counseling is now routinely offered to individuals at high risk of carrying a BRCA1 or BRCA2 mutation. Risk pred...
...BRCA2, PALB2 was sequenced in affected probands from 68 BRCA1/BRCA2-negative breast cancer families of Ashkenazi Jewish,...
...BRCA2. Interpreting the regulation of genes involved in co-expression networks, especially those involved in cancer, wil...
...BRCA2 mutation carriers (also in their normal breast cells). Our results thus indicate that the genomic instability obse...
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