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Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 bindin…

Huang(Ying),Myers(Michael P),Xu(Rui-Ming) Structure 2006-07-05

...BRCA2-interacting protein that has been implicated in the development of breast and ovarian cancer. We have determined t...

Characterization of BRCA1 and BRCA2 mutations in a large United States sample.

Chen(Sining),Iversen(Edwin S),Friebel(Tara),… J Clin Oncol 2006-03-14

An accurate evaluation of the penetrance of BRCA1 and BRCA2 mutations is essential to the identification and clinical ma...

Polymorphisms in DNA double-strand break repair genes and risk of breast cancer…

García-Closas(Montserrat),Egan(Kathleen M),N… Hum Genet 2006-09-12

...BRCA2, ZNF350, BRIP1, XRCC4, LIG4) and breast cancer risk in two population-based studies in USA (3,368 cases and 2,880 ...

The RecA binding locus of RecBCD is a general domain for recruitment of DNA str…

Spies(Maria),Kowalczykowski(Stephen C) Mol Cell 2006-04-28

...BRCA2 protein, the RecB-domain may be one of several structural domains that interact with and recruit DNA strand exchan...

Partnering in oncogenetic research--the INHERIT BRCAs experience: opportunities…

Avard(Denise),Bridge(Peter),Bucci(Lucie M),C… Fam Cancer 2006-06-22

...BRCA2 mutations and their deleterious impact upon different populations; (b) to pinpoint novel breast cancer susceptibil...

BRCA1 and BRCA2 mutations in breast and ovarian cancer syndrome: reflection on …

Sinilnikova(Olga M),Mazoyer(Sylvie),Bonnarde… Fam Cancer 2006-06-22

...BRCA2 genes, advancing the idea of the existence of other breast cancer susceptibility genes, allowing the evaluation of...

An analysis of unclassified missense substitutions in human BRCA1.

Tavtigian(Sean V),Samollow(Paul B),de Silva(… Fam Cancer 2006-06-22

...BRCA2 provides an extensible framework within which several different types of analytic data can be integrated. Among th...

Democratising access to genetic services.

Williams-Jones(Bryn),Burgess(Michael M) Fam Cancer 2006-06-22

...BRCA2 genes), this paper applies some concepts from moral philosophy to think through the effects of the commercialisati...

[Genes involved in breast cancers].

Ushijima(Toshikazu),Abe(Masanobu),Maekita(Ta… Nihon Rinsho 2006-06-06

...BRCA2 are responsible for familial breast cancers. Their somatic mutations in sporadic breast cancers are rare, but chro...

Histopathology of BRCA1- and BRCA2-associated breast cancer.

Honrado(Emiliano),Benítez(Javier),Palacios(J… Crit Rev Oncol Hematol 2006-09-20

...BRCA2-associated tumors. In addition, BRCA1- and BRCA2-associated breast carcinomas show a low frequency of HER2 express...

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