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Advances in understanding the genetic basis for bone-marrow failure.

Lieberman(Lani),Dror(Yigal) Curr Opin Pediatr 2006-05-31

...BRCA2, has been found to cause a rare subtype of Fanconi anemia.,The knowledge of the genetics of IMFSs has started to b...

Mitotic defects in XRCC3 variants T241M and D213N and their relation to cancer …

Lindh(Anna Renglin),Rafii(Saeed),Schultz(Nik… Hum Mol Genet 2006-09-19

...BRCA2 proteins. However, in contrast to mutations in BRCA1 and BRCA2, the XRCC3(T241M) protein is proficient in homologo...

Ovarian cancer and genetic susceptibility in relation to the BRCA1 and BRCA2 ge…

Søgaard(Marie),Kjaer(Susanne Krüger),Gayther… Acta Obstet Gynecol Scand 2006-04-11

...BRCA2 genes. One of the strongest risk factors for ovarian cancer is a family history of ovarian and/or early-onset brea...

[Breast cancer susceptibility genes].

Díez(Orland),Gutiérrez-Enríquez(Sara),Ramón … Med Clin (Barc) 2006-07-25

...BRCA2 genes account for less than 50% of families with breast/ovarian cancer predisposition. The large percentage of fam...

Satisfaction with genetic counseling for BRCA1 and BRCA2 mutations among Africa…

Charles(Sarah),Kessler(Lisa),Stopfer(Jill E)… Patient Educ Couns 2006-12-08

...BRCA2 (BRCA1/2) mutations among African American women.,Participants were 54 African American women at moderate and high...

Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts su…

Grabsch(Heike),Dattani(Mit),Barker(Lisa),Mau… Clin Cancer Res 2006-05-03

...BRCA2, Ku70, and Ku80 and their putative role in patients survival in a large series of colorectal cancer.,342 sporadic ...

Prognostic significance of basal-like phenotype and fascin expression in node-n…

Rodríguez-Pinilla(Socorro María),Sarrió(Davi… Clin Cancer Res 2006-05-03

...BRCA2-associated carcinomas, respectively (P = 0.048).,Basal-like tumors had a tendency towards visceral metastasis and ...

Efficacy of screening women at high risk of hereditary ovarian cancer: results …

Gaarenstroom(K N),van der Hiel(B),Tollenaar(… Int J Gynecol Cancer 2006-07-26

...BRCA2 mutation, and 127 (47%) of 269 women underwent salpingo-oophorectomy. No occult cancers were found. In eight women...

Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab …

Mann(Graham J),Thorne(Heather),Balleine(Rose… Breast Cancer Res 2006-03-21

...BRCA2 mutation positive families, but this was less evident in families in which no pathogenic BRCA1 or BRCA2 mutation h...

Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation car…

Domchek(Susan M),Friebel(Tara M),Neuhausen(S… Lancet Oncol 2006-03-28

...BRCA2 mutations. However, the reduction in mortality after this surgery is unclear. We aimed to assess whether BPSO impr...

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