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The prevalence of germline BRCA1 and BRCA2 mutations in young women with breast…

Golshan(Mehra),Miron(Alex),Nixon(Asa J),Garb… Am J Surg 2006-07-18

Germline mutations of BRCA1 and BRCA2 increase the risk for breast cancer. Mutation carriers selecting breast-conservati...

Sub-nuclear localization of Rad51 in response to DNA damage.

Mladenov(Emil),Anachkova(Boyka),Tsaneva(Irin… Genes Cells 2006-06-28

...BRCA2, but not Rad51C, with the nuclear matrix fraction in response to double-strand breaks induction. The association o...

A substantial part of the fallopian tube is left after standard prophylactic bi…

Gerritzen(L H M),Grefte(J M M),Hoogerbrugge(… Int J Gynecol Cancer 2006-11-09

...BRCA2 are candidates for bilateral salpingo-oophorectomy (BSO). To address the need for adjustment of the current BSO pr...

Application of BRCA1 and BRCA2 mutation carrier prediction models in breast and…

Oros(K K),Ghadirian(P),Maugard(C M),Perret(C… Clin Genet 2006-11-28

...BRCA2 mutation carrier status of women at high risk for developing the heritable form of breast and ovarian cancers. We ...

Contribution of germline BRCA1 and BRCA2 sequence alterations to breast cancer …

Saxena(Sunita),Chakraborty(Anurupa),Kaushal(… BMC Med Genet 2006-10-20

...BRCA2. Four previously reported polymorphisms (K1183R, S1613G, and M1652I in BRCA1, and 7470A>G in BRCA2) were detected ...

Evaluation of models to predict BRCA germline mutations.

Kang(H H),Williams(R),Leary(J),,Ringland(C),… Br J Cancer 2006-11-14

...BRCA2 assessment in the Penn model where the positive likelihood ratio was 5.93. The area under the ROC curve for each m...

Commonly studied single-nucleotide polymorphisms and breast cancer: results fro…

J Natl Cancer Inst 2006-10-10

...BRCA2 N372H, CASP8 D302H, ERCC2 D312N, IGFBP3 -202 c>a, LIG4 D501D, PGR V660L, SOD2 V16A, TGFB1 L10P, TP53 R72P, XRCC1 R...

Risk-reducing mastectomy.

Edlich(Richard F),Winters(Kathryne L),Faulkn… J Long Term Eff Med Implants 2006-12-19

...BRCA2. Correct staging of breast cancer patients is critical. It permits an accurate diagnosis, as well as in many cases...

Morphology of breast cancer as a means of triage of patients for BRCA1 genetic …

Farshid(Gelareh),Balleine(Rosemary L),Cummin… Am J Surg Pathol 2006-12-15

...BRCA2-associated breast cancer from kConFab families. After reviewing the literature, we agreed on a semiquantitative sc...

Breast cancer susceptibility testing: past, present and future.

Goldberg(Jessica I),Borgen(Patrick I) Expert Rev Anticancer Ther 2006-09-27

...BRCA2 tumor-suppressor genes. The functions of the BRCA proteins are not fully understood, although it is clear that the...

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