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Comprehensive statistical study of 452 BRCA1 missense substitutions with classi…

Tavtigian(S V),Deffenbaugh(A M),Yin(L),Judki… J Med Genet 2006-06-16

...BRCA2 testing for hereditary breast and ovarian cancer is one such widely used test. However, clinical testing methods w...

Does nonsense-mediated mRNA decay explain the ovarian cancer cluster region of …

Ware(M D),DeSilva(D),Sinilnikova(O M),Stoppa… Oncogene 2006-02-16

...BRCA2. Most BRCA2 germline mutations introduce premature termination codons (PTCs), making their mRNAs likely targets of...

Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159…

Finch(Amy),Shaw(Patricia),Rosen(Barry),Murph… Gynecol Oncol 2006-02-09

To estimate the likelihood of occult cancer diagnosis at prophylactic oophorectomy in BRCA1 and BRCA2 carriers in differ...

Hormone replacement therapy and the risk of ovarian cancer in BRCA1 and BRCA2 m…

Kotsopoulos(Joanne),Lubinski(Jan),Neuhausen(… Gynecol Oncol 2006-02-09

...BRCA2 mutation carriers who face very high lifetime risks of both breast and ovarian cancers.,We conducted a matched cas...

CA125 and transvaginal ultrasound monitoring in high-risk women cannot prevent …

Olivier(R I),Lubsen-Brandsma(M A C),Verhoef(… Gynecol Oncol 2006-02-09

...BRCA2 germ line mutation carriers, 72 members of hereditary breast and ovarian cancer (HBOC) families and 88 breast canc...

Fanconi anemia: current management.

Kook(Hoon) Hematology 2006-06-02

...BRCA2). FA-A is the most common complementation group, accounting for approximately 65% of all affected individuals. The...

Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic as…

Adsay(Nazmi Volkan),Basturk(Olca),Cheng(Jean… Semin Radiat Oncol 2006-04-18

...BRCA2 mutation, and overexpression of ki-67, 14-3-3sigma, and mesothelin. Ductal neoplasia is the most important categor...

Estradiol and its metabolites 4-hydroxyestradiol and 2-hydroxyestradiol induce …

Fernandez(Sandra V),Russo(Irma H),Russo(Jose) Int J Cancer 2006-04-18

...BRCA2. Cells treated with E2 or 4-OHE2 at doses of 0.007 and 70 nM and 2-OHE2 only at a higher dose (3.6 microM) showed ...

Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-…

Hay(Trevor),Jenkins(Helen),Sansom(Owen J),Ma… Cancer Res 2006-01-18

...Brca2 allele has not taken place. In this study, we have treated Brca2-deficient small intestine with a potent small-mol...

Breast cancer and pregnancy.

Leslie(Kimberly K),Lange(Carol A) Obstet Gynecol Clin North Am 2006-01-31

...BRCA2 are also discussed.

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