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TP53 BRCA1 CRISPR single-cell cancer

Woodward(A M),Davis(T A),Silva(A G S),Kirk(J… J Med Genet 2006-04-17

...BRCA2 in 312 index cases.,Three novel deletions detected in BRCA2 were found exclusively in families with at least one c...

Kristiansen(M),Knudsen(G P S),Maguire(P),Mar… J Med Genet 2006-07-17

...BRCA2 breast cancer (n = 272), BRCA1/BRCA2 germline mutations (n = 35), and sporadic breast cancer (n = 292).,X inactiva...

Jossé(Lyne),Harley(Margaret E),Pires(Isabel … Biochem J 2006-03-16

...BRCA2-related proteins, indicating that DSS1 has a physiological role independent of BRCA2. The DSS1 orthologue in Sacch...

van Asperen(C J),Brohet(R M),Meijers-Heijboe… J Med Genet 2006-07-27

In BRCA2 mutation carriers, increased risks have been reported for several cancer sites besides breast and ovary. As mos...

Finch(Amy),Shaw(Patricia),Rosen(Barry),Murph… Gynecol Oncol 2006-02-09

To estimate the likelihood of occult cancer diagnosis at prophylactic oophorectomy in BRCA1 and BRCA2 carriers in differ...

Kotsopoulos(Joanne),Lubinski(Jan),Neuhausen(… Gynecol Oncol 2006-02-09

...BRCA2 mutation carriers who face very high lifetime risks of both breast and ovarian cancers.,We conducted a matched cas...

Beetstra(Sasja),Salisbury(Carolyn),Turner(Ju… Carcinogenesis 2006-04-04

Mutations in BRCA1 and BRCA2 genes may cause defective DNA repair and increase the risk for breast cancer. Folate defici...

Hruban(Ralph H),Canto(Marcia I),Griffin(Cons… Curr Treat Options Gastroente… 2006-01-20

...BRCA2, STK11/LKB1, p16/CDKN2A and PRSS1 gene mutations. Individuals with one of these inherited genetic alterations and ...

Teugels(Erik),De Brakeleer(Sylvia),Goelen(Gu… Hum Mutat 2006-07-28

Linkage analysis suggests that mutations in the BRCA1 and BRCA2 genes are responsible for cancer predisposition in more ...

Kim(Young Tae),Nam(Eun Ji),Yoon(Bo Sung),Kim… Gynecol Oncol 2006-01-31

...BRCA2 genes predispose women to ovarian and/or breast cancer. The contribution of BRCA1 and BRCA2 mutations to ovarian c...

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