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TP53 BRCA1 CRISPR single-cell cancer

Cox(David G),Tamimi(Rulla M),Hunter(David J) BMC Cancer 2006-11-08

...BRCA2, and ATM can cause a substantial increase in risk of breast cancer. However, these mutations are rare in the gener...

Schmeler(Kathleen M),Sun(Charlotte C),Bodurk… Obstet Gynecol 2006-10-04

...BRCA2 mutation.,Between 1996 and 2005, 139 women who tested positive for a BRCA1 or BRCA2 mutation were identified. Thir...

Sung(Patrick),Klein(Hannah) Nat Rev Mol Cell Biol 2006-11-06

...BRCA2, which has a mediator function in HR, lead to cancer formation. DNA helicases, such as Bloom's syndrome protein (B...

Bodmer(D),Ligtenberg(M J L),van der Hout(A H… Br J Cancer 2006-12-04

...BRCA2 can be optimised by using a combination of available easy to apply risk assessment models.

Shivji(Mahmud K K),Davies(Owen R),Savill(Jan… Nucleic Acids Res 2006-09-13

...BRCA2 might fulfill these dual functions is unclear. We have purified a fragment of human BRCA2 (BRCA2(BRC1-8)) with 112...

Katki(Hormuzd A) Biometrics 2006-09-28

...BRCA2.

Clarke(C L),Sandle(J),Jones(A A),Sofronis(A)… Br J Cancer 2006-09-15

We have studied loss of heterozygosity at the BRCA1 and BRCA2 loci in 992 normal cell clones derived from topographicall...

Honrado(E),Osorio(A),Palacios(J),Benitez(J) Oncogene 2006-11-08

...BRCA2 tumors present a phenotype opposite to BRCA1 tumors but very similar to sporadic tumors, except that BRCA2 overexp...

Antoniou(A C),Easton(D F) Oncogene 2006-11-08

...BRCA2. However, it is estimated that all the currently known breast cancer susceptibility genes accounts for less than 2...

Carcangiu(Maria L),Peissel(Bernard),Pasini(B… Am J Surg Pathol 2006-10-26

The identification of germ-line mutations in 2 genes (BRCA1 and BRCA2) responsible for the majority of hereditary ovaria...

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