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Breast cancer screening, outside the population-screening program, of women fro…

Jacobi(Catharina E),Nagelkerke(Nico J D),van… Cancer Epidemiol Biomarkers P… 2006-07-19

...BRCA2 mutations, because current criteria for screening healthy women from breast cancer families are not evidence-based...

Cost-effectiveness of preventive strategies for women with a BRCA1 or a BRCA2 m…

Anderson(Kristin),Jacobson(Judith S),Heitjan… Ann Intern Med 2006-04-11

For BRCA1 or BRCA2 mutation carriers, decision analysis indicates that prophylactic surgery or chemoprevention leads to ...

Effects of oestrogens and anti-oestrogens on normal breast tissue from women be…

Bramley(M),Clarke(R B),Howell(A),Evans(D G R… Br J Cancer 2006-05-10

...BRCA2 genes. The effects of oestradiol (E2), tamoxifen (TAM) and fulvestrant (FUL) on proliferation and steroid receptor...

Haplotype analysis suggest common founders in carriers of the recurrent BRCA2 m…

Oros(Kathleen K),Leblanc(Guy),Arcand(Suzanna… BMC Med Genet 2006-06-05

The 3398delAAAAG mutation in BRCA2 was recently found to recur in breast and/or ovarian cancer families from the French ...

Screen-positive rates and agreement among six family history screening protocol…

Palomaki(Glenn E),McClain(Monica R),Steinort… Genet Med 2006-04-20

...BRCA2 genes are responsible for approximately 2% of breast cancers by age 70 years. Professional and governmental groups...

Breast and ovarian cancer in relatives of cancer patients, with and without BRC…

Lee(Jennifer S),John(Esther M),McGuire(Valer… Cancer Epidemiol Biomarkers P… 2006-06-15

...BRCA2 mutations. Ovarian cancer patients were tested for BRCA1 mutations. We estimated standardized incidence ratios (SI...

Molecular pathogenesis of Fanconi anemia: recent progress.

Taniguchi(Toshiyasu),D'Andrea(Alan D) Blood 2006-06-29

...BRCA2), appear to cooperate in a pathway leading to the recognition and repair of damaged DNA. Molecular interactions am...

Mitotic defects in XRCC3 variants T241M and D213N and their relation to cancer …

Lindh(Anna Renglin),Rafii(Saeed),Schultz(Nik… Hum Mol Genet 2006-09-19

...BRCA2 proteins. However, in contrast to mutations in BRCA1 and BRCA2, the XRCC3(T241M) protein is proficient in homologo...

Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab …

Mann(Graham J),Thorne(Heather),Balleine(Rose… Breast Cancer Res 2006-03-21

...BRCA2 mutation positive families, but this was less evident in families in which no pathogenic BRCA1 or BRCA2 mutation h...

Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation car…

Domchek(Susan M),Friebel(Tara M),Neuhausen(S… Lancet Oncol 2006-03-28

...BRCA2 mutations. However, the reduction in mortality after this surgery is unclear. We aimed to assess whether BPSO impr...

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