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The RecA binding locus of RecBCD is a general domain for recruitment of DNA str…

Spies(Maria),Kowalczykowski(Stephen C) Mol Cell 2006-04-28

...BRCA2 protein, the RecB-domain may be one of several structural domains that interact with and recruit DNA strand exchan...

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypept…

San Filippo(Joseph),Chi(Peter),Sehorn(Michae… J Biol Chem 2006-07-05

...BRCA2 DNA binding domain. The results thus clarify the role of BRCA2 in Rad51-dependent DNA recombination and repair, an...

A haplotype containing the p53 polymorphisms Ins16bp and Arg72Pro modifies canc…

Osorio(A),Martínez-Delgado(B),Pollán(M),Cuad… Hum Mutat 2006-08-02

Germline mutations in the BRCA1 and BRCA2 genes confer a high lifetime risk of developing breast and other cancers; howe...

Interaction between Arabidopsis Brca2 and its partners Rad51, Dmc1, and Dss1.

Dray(Eloïse),Siaud(Nicolas),Dubois(Emeline),… Plant Physiol 2006-05-31

...Brca2 and the two Dss1 isoforms are named AtBrca2(IV), AtBrca2(V), AtDss1(I), and AtDss1(V) after their chromosomal loca...

Population-based study of changing breast cancer risk in Icelandic BRCA2 mutati…

Tryggvadottir(Laufey),Sigvaldason(Helgi),Ola… J Natl Cancer Inst 2006-01-31

...BRCA2 founder mutation 999del5.,Information on all breast cancers diagnosed in Iceland since 1911 was obtained from the ...

BRCA1 regulates RAD51 function in response to DNA damage and suppresses spontan…

Cousineau(Isabelle),Abaji(Christine),Belmaaz… Cancer Res 2006-02-23

The breast/ovarian cancer susceptibility proteins BRCA1 and BRCA2 maintain genome stability, at least in part, through a...

[Preventive surgical prcedures for inherited risk of breast cancer].

Menke-Pluymers(M B E),Seynaeve(C),van Geel(A… Ned Tijdschr Geneeskd 2006-01-10

...BRCA2 mutation, the cumulative risk of developing invasive breast cancer before the age of 70 years is about 50-85% and ...

[Management of gynecological tumors associated with BRCA1 and BRCA2 germline mu…

Fruscalzo(A),Lellé(R J),Calcagno(A),Driul(L)… Minerva Ginecol 2006-11-01

Genetic investigation of BRCA1 and BRCA2 germline mutations is, nowadays, a diagnostic procedure with practical clinical...

Assessing the link between BACH1 and BRCA1 in the FA pathway.

Cantor(Sharon B),Andreassen(Paul R) Cell Cycle 2006-04-28

...BRCA2/FANCD1. Interestingly, while BRCA1 has various interactions with FA proteins it has not been identified as an FA g...

Association of DNA repair and steroid metabolism gene polymorphisms with clinic…

Damaraju(Sambasivarao),Murray(David),Dufour(… Clin Cancer Res 2006-10-30

...BRCA2, ESR1, XRCC1, XRCC2, XRCC3, NBN, RAD51, RAD52, LIG4, ATM, BCL2, TGFB1, MSH6, ERCC2, XPF, NR3C1, CYP1A1, CYP2C9, CY...

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