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TP53 BRCA1 CRISPR single-cell cancer

Domchek(Susan M),Stopfer(Jill E),Rebbeck(Tim… J Natl Compr Canc Netw 2006-05-26

...BRCA2 (BRCA1/2) mutations. BRRO significantly reduces breast cancer risk by approximately 50% and ovarian cancer risk by...

Mitchell(Gillian),Antoniou(Antonis C),Warren… Cancer Res 2006-03-21

...BRCA2 mutations is unclear. We obtained mammograms from 206 female carriers of BRCA1 or BRCA2 mutations, 96 of whom were...

Daum(Hagit),Sagi(Michal),Pikarsky(Eli),Pruss… Harefuah 2006-03-02

...BRCA2 were cloned. Mutations in each gene are responsible for the syndrome of familial breast and ovarian carcinoma. Amo...

Dray(Eloïse),Siaud(Nicolas),Dubois(Emeline),… Plant Physiol 2006-05-31

...Brca2 and the two Dss1 isoforms are named AtBrca2(IV), AtBrca2(V), AtDss1(I), and AtDss1(V) after their chromosomal loca...

James(Paul A),Doherty(Rebecca),Harris(Marion… J Clin Oncol 2006-02-13

...BRCA2 genes. We examined the performance of six different methods with the aim of identifying an optimal strategy for se...

Bramley(M),Clarke(R B),Howell(A),Evans(D G R… Br J Cancer 2006-05-10

...BRCA2 genes. The effects of oestradiol (E2), tamoxifen (TAM) and fulvestrant (FUL) on proliferation and steroid receptor...

Glazko(Galina V),Babenko(Vladimir N),Koonin(… Biol Direct 2006-04-26

...BRCA2, and p16. Elucidation of the origin of the hotspots in these genes requires more data on somatic mutations in tumo...

Simchoni(Sharon),Friedman(Eitan),Kaufman(Bel… Proc Natl Acad Sci U S A 2006-04-17

Inherited mutations in BRCA1 and BRCA2 lead to significantly increased risks of breast and ovarian cancer. We used epide...

Jacobi(Catharina E),Nagelkerke(Nico J D),van… Cancer Epidemiol Biomarkers P… 2006-07-19

...BRCA2 mutations, because current criteria for screening healthy women from breast cancer families are not evidence-based...

Anderson(Kristin),Jacobson(Judith S),Heitjan… Ann Intern Med 2006-04-11

For BRCA1 or BRCA2 mutation carriers, decision analysis indicates that prophylactic surgery or chemoprevention leads to ...

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