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Bilateral risk-reducing oophorectomy in BRCA1 and BRCA2 mutation carriers.

Domchek(Susan M),Stopfer(Jill E),Rebbeck(Tim… J Natl Compr Canc Netw 2006-05-26

...BRCA2 (BRCA1/2) mutations. BRRO significantly reduces breast cancer risk by approximately 50% and ovarian cancer risk by...

Nipple aspiration and ductal lavage in women with a germline BRCA1 or BRCA2 mut…

Mitchell(Gillian),Antill(Yoland C),Murray(Wi… Breast Cancer Res 2006-02-27

...BRCA2 mutations (median age 43 years, range 27 to 65 years) were scheduled for six-monthly NA, DL and venesection. DL wa...

The significance of cytological mesothelial atypia diagnosed from peritoneal wa…

Eitan(Ram),Soslow(Robert),Lin(Oscar),Kauff(N… Gynecol Oncol 2006-08-29

...BRCA2 mutation were found to have mesothelial atypia compared to 1 (8%) of 12 with no mutation. With a median follow-up ...

BRCA1 and BRCA2 mutation screening using SmartCycler II high-resolution melt cu…

Dufresne(Scott D),Belloni(Dorothy R),Wells(W… Arch Pathol Lab Med 2006-02-23

...BRCA2.,Real-time polymerase chain reaction amplification with SYBR Green I detection was performed on DNA from cell line...

BRCA1 and BRCA2 mutation predictions using the BOADICEA and BRCAPRO models and …

Antoniou(Antonis C),Durocher(Francine),Smith… Breast Cancer Res 2006-03-21

...BRCA2 penetrance analysis.,The BOADICEA model predicted accurately the number of BRCA1 and BRCA2 mutations for the vario...

Lower level of BRCA2 protein in heterozygous mutation carriers is correlated wi…

Arnold(Katrin),Kim(Min-Kyoung),Frerk(Katrin)… Cancer Lett 2006-12-06

...BRCA2+/- cells showed lower amounts of the full-length BRCA2 protein compared to BRCA2+/+ cells. The kinetics of gamma-H...

Prophylactic salpingo-oophorectomy in 51 women with familial breast-ovarian can…

Leunen(K),Legius(E),Moerman(P),Amant(F),Neve… Int J Gynecol Cancer 2006-05-17

...BRCA2 patient; discrete focal atypia of tubal and ovarian epithelium in a patient with a negative BRCA1/BRCA2 mutation a...

Establishment of three human breast epithelial cell lines derived from carriers…

Rubner Fridriksdottir(Agla J),Gudjonsson(Tho… In Vitro Cell Dev Biol Anim 2006-10-05

...BRCA2-999del5-2T and BRCA2-999del5-2N, respectively. In addition, one cell line was derived from cancer-associated norma...

Genetic factors in ovarian carcinoma.

Li(A J),Karlan(B Y) Curr Oncol Rep 2005-05-18

...BRCA2; mismatch repair genes such as hMSH2 and hMLH1; and PTEN, HER-2/neu, K-ras, fms, and AKT2. Novel genes recently im...

[BRCA2 gene mutation detection in hereditary ovarian cancer tissues].

Qiao(Yuhuan),Chen(Ping),Shi(Huirong),Zhao(Gu… Zhonghua Fu Chan Ke Za Zhi 2005-01-25

...BRCA2 gene. The mutation type was 6174del T in the 11 exon of BRCA2 gene. No mutation of BRCA2 gene on this site was fou...

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