...BRCA2 founder mutations in a large cohort of 154 MBC patients (65% diagnosed in Finland from 1967 to 1996). Founder muta...
...BRCA2 are tumor suppressor genes, the mutant phenotypes of which predispose to breast and ovarian cancers. Intensive res...
...BRCA2 and STK11, which additional studies have shown also carry an increased risk of pancreatic cancer. However, these k...
...BRCA2, but the biochemical functions of other FA proteins are largely unknown. By constructing and characterizing a null...
...BRCA2 negative families and families with a history of bilateral disease or male breast cancer. However, the 1100delC mu...
...BRCA2 are the most important. Mutations in these genes confer high lifetime risks of breast cancer and ovarian cancer, a...
...BRCA2 . Early discoveries that the two genes function in the control of homologous recombination and the prevention of g...
The objective of this study was to determine the prevalence of BRCA1 and BRCA2 gene mutations in unselected ovarian canc...
...BRCA2 mutation.
Women who carry deleterious mutations of BRCA1 or BRCA2 genes have up to a 54% lifetime risk of developing ovarian cance...
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