...BRCA2 unclassified variants (UCV), including missense mutations and in-frame deletions and insertions on BRCA2 function ...
...BRCA2, HER2 and p53, in the development of breast cancer and their clinical implications.
...BRCA2 gene encodes a large multidomain protein of 3418 residues. Studies to elucidate the mechanisms by which BRCA2 prev...
...BRCA2) and D2. We have previously reported an increased incidence of epithelial tumors in Fancd2 knockout mice. To furth...
...BRCA2 has been thought to be rare in breast cancers, though common allelic deletions in the BRCA2 locus (13q12-q13) impl...
...BRCA2; low-grade serous carcinomas probably arise in a stepwise fashion in an adenoma-borderline tumor-carcinoma sequenc...
...BRCA2 mutations account for a substantial proportion of familial breast cancer, but clearly mutations in additional gene...
...BRCA2 susceptibility genes. No "BRCA3" gene has been found to account for the non-BRCA1/BRCA2 breast cancer (BRCAx) fami...
...BRCA2 mutated breast tumors. Overexpression of Tbx2 and the related factor Tbx3, which is also overexpressed in breast c...
...BRCA2, p53, PTEN, ATM, NBS1 or LKB1) and low-penetrance genes such as cytochrome P450 genes (CYP1A1, CYP2D6, CYP19), glu...
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