Since the discovery of the tumour suppressor BRCA2 (encoded by breast-cancer susceptibility gene 2), cells lacking the f...
...Brca2 (brca2lex1/lex2) or Blm (blm(tm3Brd/tm4Brd)), are hypersensitive to TSA in a dose-dependent manner. TSA-induced to...
...BRCA2, AR and MSH2. No sequence variant has been detected by direct genomic sequencing of exon 13A in individuals origin...
...BRCA2 and BAX are not regulated appropriately and protease activation is delayed. Furthermore, expression of MMP3 and C/...
...BRCA2 genes, 20 cases with BRCA1 mutation, 20 cases of sporadic ovarian cancer, and 19 controls were screened for mutati...
Ten years after BRCA1 and BRCA2 were first identified as major breast cancer susceptibility genes, the spectrum of mutat...
...BRCA2 mutations and to determine to what extent risk reduction varies with age at oophorectomy, age at diagnosis, and ti...
...BRCA2 and non-BRCA1/2 tumors, but have not identified differences between BRCA2 and non-BRCA1/2 tumors. Because BRCA1 an...
...BRCA2 (BRCA1/2) as well as genes TP53 and PTEN. Since 1996, genetic testing for these mutations has been clinically avai...
...BRCA2). Issues addressed touch on the evolution of the subfield, its potential impact on cancer treatment, and industry ...
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