...BRCA2, ATM, ...) and somatic (p53, tyrosine kinase receptors, as well as actors of cell cycle, signal transduction, apop...
...BRCA2 mutations predispose to the development of pancreatic cancer. A polymorphic stop codon in the coding region of BRC...
...BRCA2 (BRCA1/2) mutations and explore testing intentions in African American women at increased risk for hereditary brea...
...BRCA2 mutant cells. We exploit this requirement in order to kill BRCA2-deficient tumours by PARP inhibition alone. Treat...
BRCA1 and BRCA2 are important for DNA double-strand break repair by homologous recombination, and mutations in these gen...
BRCA2 was identified in 1995, one year after BRCA1. In terms of knowledge of the function of its product, BRCA2 has rema...
...BRCA2 testing. Physician recommendation for BRCA1/BRCA2 testing and indecision about definitive local treatment were bot...
Inherited mutations in BRCA2 are associated with a predisposition to early-onset breast cancers. The underlying basis of...
...BRCA2 (n=9) and a group of healthy mutation carriers (n=12) was investigated and compared to a reference group of breast...
...BRCA2, n = 19; both, n = 1), and 46 with a mutation (BRCA1, n = 32; BRCA2, n = 14). Two of the UVs were novel variants; ...
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