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Additional salpingectomy after previous prophylactic oophorectomy in high-risk …

Olivier(Roelien I),Lubsen-Brandsma(Lottie A … Gynecol Oncol 2005-03-03

...BRCA2 carrier, one BRCA1 and 2 carrier, and three women with non-informative test results. The procedure was readily don...

The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA ju…

Yang(Haijuan),Li(Qiubai),Fan(Jie),Holloman(W… Nature 2005-03-03

...BRCA2 in repair has been unclear. Here we show that a full-length BRCA2 homologue (Brh2) stimulates Rad51-mediated recom...

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumo…

van Beers(Erik H),van Welsem(Tibor),Wessels(… Cancer Res 2005-03-14

...BRCA2 are both implicated in DNA repair and genome stability, it is unknown whether BRCA1 and BRCA2 are associated with ...

BRCA2 in meiosis: turning over a new leaf.

Gudmundsdottir(Katrin),Ashworth(Alan) Trends Cell Biol 2005-01-25

...BRCA2-like genes in the plant Arabidopsis thaliana have a key role in meiosis. Investigating BRCA2 in distantly related ...

Penetrances of breast and ovarian cancer in a large series of families tested f…

Marroni(Fabio),Aretini(Paolo),D'Andrea(Emma)… Eur J Hum Genet 2005-05-11

...BRCA2 carriers, and ovarian cancer penetrances were 14% (7-22%) at age 50 and 43% (21-66%) at age 70 in BRCA1 carriers a...

Common variation in BRCA2 and breast cancer risk: a haplotype-based analysis in…

Freedman(Matthew L),Penney(Kathryn L),Stram(… Hum Mol Genet 2005-04-25

...BRCA2 among women in the Multiethnic Cohort Study (MEC), genotyping 50 SNPs spanning 109.4 kb of the BRCA2 gene. Twenty-...

BRCA1 and BRCA2 germline mutations in Korean patients with sporadic breast canc…

Seo(Jae Hong),Cho(Dae-Yeon),Ahn(Se-Hyun),Yoo… Hum Mutat 2005-03-31

...BRCA2 mutation (c.2259delT) were observed, and two of these (BRCA1 c.5445G>A and BRCA2 c.2259delT) are novel. The total ...

BRCA1 mutations in a population-based study of breast cancer in Stockholm Count…

Margolin(Sara),Werelius(Barbro),Fornander(To… Genet Test 2005-02-04

The mutation frequency of BRCA1 and BRCA2 in women with breast cancer varies according to family history, age at diagnos...

Amplification of the BRCA2 pathway gene EMSY in sporadic breast cancer is relat…

Rodriguez(Carmen),Hughes-Davies(Luke),Vallès… Clin Cancer Res 2005-02-15

...BRCA2 and has a role in chromatin remodeling. This makes EMSY a strong candidate oncogene for the 11q13.5 amplicon. DNA ...

DSS1 is required for RAD51 focus formation and genomic stability in mammalian c…

Gudmundsdottir(Katrin),Lord(Christopher J),W… EMBO Rep 2005-04-11

...BRCA2 or RAD51 stability or for BRCA2 and RAD51 to interact, raising the possibility that DSS1 may be required for the B...

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