Identifying BRCA1 and BRCA2 mutation carriers is increasingly important as new management options show promise in decrea...
BRCA1 and BRCA2 germline mutations are associated with a strong risk of breast cancer, which may preclude breast-conserv...
...BRCA2 3' (mRNA pool), BRCA1 ex11 (with exon 11), BRCA2 ex12 (with exon 12) and hMSH2 mRNAs were increased in tumor sampl...
Mutations in BRCA1 and BRCA2 account for a significant proportion of hereditary breast cancers. Earlier studies have sho...
...BRCA2 repair foci. These data do not support a threshold model for activation of DNA repair in hyper-radiosensitive cell...
...BRCA2 genes are associated with increased susceptibility for breast and ovarian cancer. Although these mutations are unc...
The EMSY gene encodes a protein that interacts with Brca2 and is amplified in some sporadic cases of human breast cancer...
...BRCA2 gene. In deciding whether women with germ-line mutations in the BRCA1 gene should use oral contraceptives a possib...
The clinical outcome of contralateral prophylactic mastectomy (CPM) in women with a BRCA1 or BRCA2 mutation and a person...
Since the discovery of the tumour suppressor BRCA2 (encoded by breast-cancer susceptibility gene 2), cells lacking the f...
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