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DNA recombination, chromosomal stability and carcinogenesis: insights into th...

Shivji(Mahmud K K),Venkitaraman(Ashok R) DNA Repair (Amst) 2005-02-14

Germline mutations affecting a single allele of BRCA2 increase susceptibility to breast and ovarian cancer, whilst germl...

The interplay of Fanconi anemia proteins in the DNA damage response.

Wang(XiaoZhe),D'Andrea(Alan D) DNA Repair (Amst) 2005-02-14

...BRCA2 in damaged chromatin. Disruption of this pathway results in the clinical and cellular abnormalities common to all ...

Genetic alterations in hereditary breast cancer.

Cipollini(G),Tommasi(S),Paradiso(A),Aretin... Ann Oncol 2005-01-05

...BRCA2, but also CHK2, ATM, STK11 and others. This paper examines the BRCA1 and BRCA2 genes, focusing on the Italian patt...

External quality assessment for mutation detection in the BRCA1 and BRCA2 gen...

Mueller(C R),Kristoffersson(U),Stoppa-Lyon... Ann Oncol 2005-01-05

...BRCA2, designed to cover the two important aspects of genetic testing: (i) genotyping and (ii) interpretation and report...

Reducing breast cancer incidence in familial breast cancer: overlooking the p...

Marchetti(P),Di Rocco(C Z),Ricevuto(E),Bis... Ann Oncol 2005-01-05

...BRCA2 (BRCA1/2) gene analysis in women accrued in the NSABP-P1 trial who developed breast cancer showed that tamoxifen c...

Decisions and outcomes of genetic testing for inherited breast cancer risk.

Halbert(C H) Ann Oncol 2005-01-05

...BRCA2 (BRCA1/2) genetic test results. This article explores findings related to genetic test acceptance for inherited br...

Genetic testing and breast cancer: the women's point of view.

Mosconi(P),Leccese(A) Ann Oncol 2005-01-05

...BRCA2 mutations is largely debated, in particular regarding patient counseling, and psychosocial and legislative support...

Intensive radiologic surveillance: a focus on the psychological issues.

Warner(E) Ann Oncol 2005-01-05

...BRCA2 mutations have up to an 85% lifetime risk of breast cancer, the majority choose to forego prophylactic mastectomy,...

Molecular functions of BRCA1 in the DNA damage response.

Scully(Ralph),Xie(Anyong),Nagaraju(Ganesh) Cancer Biol Ther 2005-05-19

...BRCA2 and other genes to control double strand break repair (DSBR) and homologous recombination. Here, we reassess the r...

Suppression of retroviral infection by the RAD52 DNA repair protein.

Lau(Alan),Kanaar(Roland),Jackson(Stephen P... EMBO J 2005-06-14

...BRCA2) do not markedly affect retroviral transduction rates, suggesting that the HR repair pathway per se does not influ...

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