Women with a germline BRCA1 or BRCA2 mutation have a significantly increased risk of developing ovarian cancer compared ...
...BRCA2). Mutations in the FANCA gene are the most prevalent, accounting for two-thirds of FA cases. Affected individuals ...
Biallelic mutations in BRCA2/FANCD1 were recently recognized as a rare cause of Fanconi anemia (FA). Using immunodetecti...
...BRCA2, but is also attributable to another gene in this region. There is strong indication of a new tumor suppressor gen...
...BRCA2 with, as additional examples, 188del11 and 5396 + 1G --> A in BRCA1. Our HA method is based upon the use of a repl...
...BRCA2 are involved in DNA repair. To evaluate further the role of DNA repair in breast cancer we determined: (1) the kin...
...BRCA2, in 1994 and 1995 and the subsequent development of commercial genetic testing has brought hereditary cancer genet...
...BRCA2 mutation, can present itself with ovarian cancer only. In three women, 43, 50 and 61 years of age, there was a fam...
...BRCA2 was suggested to underlie complementation group B, but the evidence is inconclusive. Here we show that the protein...
...BRCA2 mutation in our study subjects was estimated using the BRCAPRO. Parameters were compared using either the chi(2) o...
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